Recombinant Full Length Human ADIPOR1 Protein, C-Flag-tagged

• Cat.No.: ADIPOR1-691HFL
• Product Overview: Recombinant Full Length Human ADIPOR1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 42.4 kDa
• AA Sequence: MSSHKGSVVAQGNGAPASNREADTV ELAELGPLLEEKGKRVIANPPKAEE EQTCPVPQEEEEEVRVLTLP LQAHHAMEKMEEFVYKVWEGRWRVI PYDVLPDWLKDNDYLLHGHRPPMPS FRACFKSIFRIHTETGNIWT HLLGFVLFLFLGILTMLRPNMYFMA PLQEKVVFGMFFLGAVLCLSFSWLF HTVYCHSEKVSRTFSKLDYS GIALLIMGSFVPWLYYSFYCSPQPR LIYLSIVCVLGISAIIVAQWDRFAT PKHRQTRAGVFLGLGLSGVV PTMHFTIAEGFVKATTVGQMGWFFL MAVMYITGAGLYAARIPERFFPGKF DIWFQSHQIFHVLVVAAAFV
  HFYGVSNLQEFRYGLEGGCTDDTLL TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Adipocytokine signaling pathway

Gene Information

• Gene Name: ADIPOR1 adiponectin receptor 1 [ Homo sapiens (human) ]
• Official Symbol: ADIPOR1
• Synonyms: CGI45; PAQR1; ACDCR1; CGI-45; TESBP1A
• Gene ID: 51094
• mRNA Refseq: NM_015999.6
• Protein Refseq: NP_057083.2
• MIM: 607945
• UniProt ID: Q96A54