Recombinant Full Length Human ATP6AP1 Protein, GST-tagged

• Cat.No.: ATP6AP1-1542HF
• Product Overview: Human ATP6AP1 full-length ORF ( NP_001174.2, 1 a.a. - 470 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 78.4 kDa
• Protein Length: 470 amino acids
• AA Sequence: MMAAMATARV RMGPRCAQAL WRMPWLPVFL SLAAAAAAAA AEQQVPLVLW SSDRDLWAPA ADTHEGHITS DLQLSTYLDP ALELGPRNVL LFLQDKLSIE DFTAYGGVFG NKQDSAFSNL ENALDLAPSS LVLPAVDWYA VSTLTTYLQE KLGASPLHVD LATLRELKLN ASLPALLLIR LPYTASSGLM APREVLTGND EVIGQVLSTL KSEDVPYTAA LTAVRPSRVA RDVAVVAGGL GRQLLQKQPV SPVIHPPVSY NDTAPRILFW AQNFSVAYKD QWEDLTPLTF GVQELNLTGS FWNDSFARLS LTYERLFGTT VTFKFILANR LYPVSARHWF TMERLEVHSN GSVAYFNASQ VTGPSIYSFH CEYVSSLSKK GSLLVARTQP SPWQMMLQDF QIQAFNVMGE QFSYASDCAS FFSPGIWMGL LTSLFMLFIF TYGLHMILSL KTMDRFDDHK GPTISLTQIV
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 [ Homo sapiens ]
• Official Symbol: ATP6AP1
• Synonyms: ATP6AP1; ATPase, H+ transporting, lysosomal accessory protein 1; ATP6IP1, ATP6S1, ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1; V-type proton ATPase subunit S1; 16A; Ac45; CF2; ORF; VATPS1; XAP 3; XAP3; protein XAP-3; H-ATPase subunit; V-ATPase subunit S1; V-ATPase Ac45 subunit; V-ATPase S1 accessory protein; vacuolar proton pump subunit S1; ATPase, H+ transporting, lysosomal interacting protein 1; ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1; XAP-3; ATP6S1; ATP6IP1; MGC129781
• Gene ID: 537
• mRNA Refseq: NM_001183
• Protein Refseq: NP_001174
• MIM: 300197
• UniProt ID: Q15904