Recombinant Full Length Human ATRX Protein, GST-tagged
Cat.No. : | ATRX-1535HF |
Product Overview : | Human ATRX full-length ORF ( AAH02521, 1 a.a. - 90 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2013] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 35.53 kDa |
Protein Length : | 90 amino acids |
AA Sequence : | MTAEPMSESK LNTLVQKLHD FLAHSSEESE ETSSPPRLAM NQNTDKISGS GSNSDMMENS KEEGTSSSEK SKSSGSSRSK RKPSIVNKND |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ATRX alpha thalassemia/mental retardation syndrome X-linked [ Homo sapiens ] |
Official Symbol : | ATRX |
Synonyms : | ATRX; alpha thalassemia/mental retardation syndrome X-linked; alpha thalassemia/mental retardation syndrome X linked (RAD54 (S. cerevisiae) homolog) , JMS, Juberg Marsidi syndrome , RAD54; transcriptional regulator ATRX; RAD54 homolog (S. cerevisiae); XH2; XNP; RAD54 homolog; X-linked helicase II; Zinc finger helicase; helicase 2, X-linked; X-linked nuclear protein; ATP-dependent helicase ATRX; DNA dependent ATPase and helicase; alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae); JMS; SHS; ATR2; SFM1; RAD54; MRXHF1; RAD54L; ZNF-HX; MGC2094 |
Gene ID : | 546 |
mRNA Refseq : | NM_000489 |
Protein Refseq : | NP_000480 |
MIM : | 300032 |
UniProt ID : | P46100 |
Products Types
◆ Recombinant Protein | ||
ATRX-898M | Recombinant Mouse ATRX Protein, His (Fc)-Avi-tagged | +Inquiry |
ATRX-150H | Recombinant Human ATRX protein, GST-tagged | +Inquiry |
ATRX-1289H | Recombinant Human ATRX protein, His-SUMO-tagged | +Inquiry |
ATRX-1028H | Recombinant Human ATRX protein, GST-tagged | +Inquiry |
ATRX-10066H | Recombinant Human ATRX protein, His-tagged | +Inquiry |
◆ Lysates | ||
ATRX-150HCL | Recombinant Human ATRX cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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