Recombinant Full Length Human BCKDK Protein, GST-tagged

• Cat.No.: BCKDK-1577HF
• Product Overview: Human BCKDK full-length ORF ( AAH07363, 28 a.a. - 412 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine, leucine, and isoleucine catabolic pathways. The protein encoded by this gene is found in the mitochondrion, where it phosphorylates and inactivates BCKD. Several transcript variants encoding different isoforms have been found for this gene.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 68.09 kDa
• Protein Length: 28-412 amino acids
• AA Sequence: RARSTSATDT HHVEMARERS KTVTSFYNQS AIDAAAEKPS VRLTPTMMLY AGRSQDGSHL LKSARYLQQE LPVRIAHRIK GFRCLPFIIG CNPTILHVHE LYIRAFQKLT DFPPIKDQAD EAQYCQLVRQ LLDDHKDVVT LLAEGLRESR KHIEDEKLVR YFLDKTLTSR LGIRMLATHH LALHEDKPDF VGIICTRLSP KKIIEKWVDF ARRLCEHKYG NAPRVRINGH VAARFPFIPM PLDYILPELL KNAMRATMES HLDTPYNVPD VVITIANNDV DLIIRISDRG GGIAHKDLDR VMDYHFTTAE ASTQDPRISP LFGHLDMHSG AQSGPMHGFG FGLPTSRAYA EYLGGSLQLQ SLQGIGTDVY LRLRHIDGRE ESFRI
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: BCKDK branched chain ketoacid dehydrogenase kinase [ Homo sapiens ]
• Official Symbol: BCKDK
• Synonyms: BCKDK; branched chain ketoacid dehydrogenase kinase; [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; BCKDHKIN; BCKD-kinase; branched chain alpha-ketoacid dehydrogenase kinase; branched-chain alpha-ketoacid dehydrogenase kinase
• Gene ID: 10295
• mRNA Refseq: NM_001122957
• Protein Refseq: NP_001116429
• MIM: 614901
• UniProt ID: O14874