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Recombinant Full Length Human BIRC2 Protein, C-Flag-tagged

Cat.No. : BIRC2-954HFL
Product Overview : Recombinant Full Length Human BIRC2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source : Mammalian cells
Species : Human
Tag : Flag
Form : 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 69.7 kDa
AA Sequence : MHKTASQRLFPGPSYQNIKSIMEDS TILSDWTNSNKQKMKYDFSCELYRM STYSTFPAGVPVSERSLARA GFYYTGVNDKVKCFCCGLMLDNWKL GDSPIQKHKQLYPSCSFIQNLVSAS LGSTSKNTSPMRNSFAHSLS PTLEHSSLFSGSYSSLSPNPLNSRA VEDISSSRTNPYSYAMSTEEARFLT YHMWPLTFLSPSELARAGFY YIGPGDRVACFACGGKLSNWEPKDD AMSEHRRHFPNCPFLENSLETLRFS ISNLSMQTHAARMRTFMYWP SSVPVQPEQLASAGFYYVGRNDDVK CFCCDGGLRCWESGDDPWVEHAKWF PRCEFLIRMKGQEFVDEIQG RYPHLLEQLLSTSDTTGEENADPPI IHFGPGESSSEDAVMMNTPVVKSAL EMGFNRDLVKQTVQSKILTT GENYKTVNDIVSALLNAEDEKREEE KEKQAEEMASDDLSLIRKNRMALFQ QLTCVLPILDNLLKANVINK QEHDIIKQKTQIPLQARELIDTILV KGNAAANIFKNCLKEIDSTLYKNLF VDKNMKYIPTEDVSGLSLEE
QLRRLQEERTCKVCMDKEVSVVFIP CGHLVVCQECAPSLRKCPICRGIIK GTVRTFLSTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining.
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 ug/mL as determined by microplate BCA method.
Preparation : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families : Druggable Genome
Protein Pathways : Apoptosis, Focal adhesion, NOD-like receptor signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis
Gene Name : BIRC2 baculoviral IAP repeat containing 2 [ Homo sapiens (human) ]
Official Symbol : BIRC2
Synonyms : API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1
Gene ID : 329
mRNA Refseq : NM_001166.5
Protein Refseq : NP_001157.1
MIM : 601712
UniProt ID : Q13490

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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