Recombinant Full Length Human C3AR1 Protein, C-Flag-tagged

• Cat.No.: C3AR1-694HFL
• Product Overview: Recombinant Full Length Human C3AR1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 53.7 kDa
• AA Sequence: MASFSAETNSTDLLSQPWNEPPVIL SMVILSLTFLLGLPGNGLVLWVAGL KMQRTVNTIWFLHLTLADLL CCLSLPFSLAHLALQGQWPYGRFLC KLIPSIIVLNMFASVFLLTAISLDR CLVVFKPIWCQNHRNVGMAC SICGCIWVVAFVMCIPVFVYREIFT TDNHNRCGYKFGLSSSLDYPDFYGD PLENRSLENIVQPPGEMNDR LDPSSFQTNDHPWTVPTVFQPQTFQ RPSADSLPRGSARLTSQNLYSNVFK PADVVSPKIPSGFPIEDHET SPLDNSDAFLSTHLKLFPSASSNSF YESELPQGFQDYYNLGQFTDDDQVP TPLVAITITRLVVGFLLPSV IMIACYSFIVFRMQRGRFAKSQSKT FRVAVVVVAVFLVCWTPYHIFGVLS LLTDPETPLGKTLMSWDHVC
  IALASANSCFNPFLYALLGKDFRKK ARQSIQGILEAAFSEELTRSTHCPS NNVISERNSTTVTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Complement and coagulation cascades, Neuroactive ligand-receptor interaction

Gene Information

• Gene Name: C3AR1 complement C3a receptor 1 [ Homo sapiens (human) ]
• Official Symbol: C3AR1
• Synonyms: AZ3B; C3AR; HNFAG09
• Gene ID: 719
• mRNA Refseq: NM_004054.4
• Protein Refseq: NP_004045.1
• MIM: 605246
• UniProt ID: Q16581