Recombinant Full Length Human CACNB3 Protein, C-Flag-tagged

• Cat.No.: CACNB3-1450HFL
• Product Overview: Recombinant Full Length Human CACNB3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a regulatory beta subunit of the voltage-dependent calcium channel. Beta subunits are composed of five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 54.4 kDa
• AA Sequence: MYDDSYVPGFEDSEAGSADSYTSRP SLDSDVSLEEDRESARREVESQAQQ QLERAKHKPVAFAVRTNVSY CGVLDEECPVQGSGVNFEAKDFLHI KEKYSNDWWIGRLVKEGGDIAFIPS PQRLESIRLKQEQKARRSGN PSSLSDIGNRRSPPPSLAKQKQKQA EHVPPYDVVPSMRPVVLVGPSLKGY EVTDMMQKALFDFLKHRFDG RISITRVTADLSLAKRSVLNNPGKR TIIERSSARSSIAEVQSEIERIFEL AKSLQLVVLDADTINHPAQL AKTSLAPIIVFVKVSSPKVLQRLIR SRGKSQMKHLTVQMMAYDKLVQCPP ESFDVILDENQLEDACEHLA EYLEVYWRATHHPAPGPGLLGPPSA IPGLQNQQLLGERGEEHSPLERDSL MPSDEASESSRQAWTGSSQR
  SSRHLEEDYADAYQDLYQPHRQHTS GLPSANGHDPQDRLLAQDSEHNHSD RNWQRNRPWPKDSYTRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Ion Channels: Other
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway

Gene Information

• Gene Name: CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 [ Homo sapiens (human) ]
• Official Symbol: CACNB3
• Synonyms: CAB3; CACNLB3
• Gene ID: 784
• mRNA Refseq: NM_000725.4
• Protein Refseq: NP_000716.2
• MIM: 601958
• UniProt ID: P54284