Recombinant Full Length Human CD207 Protein, GST-tagged

Cat.No. : CD207-3016HF
Product Overview : Human CD207 full-length ORF (AAH22278, 1 a.a. - 328 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010]
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 61.82 kDa
Protein Length : 328 amino acids
AA Sequence : MTVEKEAPDAHFTVDKQNISLWPRE PPPKSGPSLVPGKTPTVRAALICLT LVLVASVLLQAVLYPRFMGTISDVK TNVQLLKGRVDNISTLDSEIKKNSD GMEAAGVQIQMVNESLGYVRSQFLK LKTSVEKANAQIQILTRSWEEVSTL NAQIPELKSDLEKASALNTKIRALQ GSLENMSKLLKRQNDILQVVSQGWK YFKGNFYYFSLIPKTWYSAEQFCVS RNSHLTSVTSESEQEFLYKTAGGLI YWIGLTKAGMEGDWSWVDDTPFNKV QSARFWIPGEPNNAGNNEHCGNIKA PSLQAWNDAPCDKTFLFICKRPYVP SEP
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CD207 CD207 molecule, langerin [ Homo sapiens ]
Official Symbol : CD207
Synonyms : CD207; CD207 molecule, langerin; CD207 antigen, langerin; C-type lectin domain family 4 member K; CLEC4K; Langerin; Langerhans cell specific c-type lectin; C-type lectin domain family 4, member K;
Gene ID : 50489
mRNA Refseq : NM_015717
Protein Refseq : NP_056532
MIM : 604862
UniProt ID : Q9UJ71

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