Recombinant Full Length Human CD3D Protein, GST-tagged
Cat.No. : | CD3D-3173HF |
Product Overview : | Human CD3D full-length ORF (NP_000723.1, 1 a.a. - 171 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 45.3 kDa |
Protein length : | 171 amino acids |
AA Sequence : | MEHSTFLSGLVLATLLSQVSPFKIP IEELEDRVFVNCNTSITWVEGTVGT LLSDITRLDLGKRILDPRGIYRCNG TDIYKDKESTVQVHYRMCQSCVELD PATVAGIIVTDVIATLLLALGVFCF AGHETGRLSGAADTQALLRNDQVYQ PLRDRDDAQYSHLGGNWARNK |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CD3D CD3d molecule, delta (CD3-TCR complex) [ Homo sapiens ] |
Official Symbol : | CD3D |
Synonyms : | CD3D; CD3d molecule, delta (CD3-TCR complex); CD3d antigen, delta polypeptide (TiT3 complex), T3D; T-cell surface glycoprotein CD3 delta chain; CD3 delta; OKT3, delta chain; CD3 antigen, delta subunit; T-cell receptor T3 delta chain; CD3d antigen, delta polypeptide (TiT3 complex); T3D; CD3-DELTA; |
Gene ID : | 915 |
mRNA Refseq : | NM_000732 |
Protein Refseq : | NP_000723 |
MIM : | 186790 |
UniProt ID : | P04234 |
Products Types
◆ Lysates | ||
CD3D-1274HCL | Recombinant Human CD3D cell lysate | +Inquiry |
CD3D-1381MCL | Recombinant Mouse CD3D cell lysate | +Inquiry |
CD3D-1466CCL | Recombinant Cynomolgus CD3D cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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