Recombinant Full Length Human CDX2 Protein

• Cat.No.: CDX2-75HF
• Product Overview: Recombinant full length Human CDX2 with N terminal proprietary tag, 60.54kDa.

Specification

• Description: The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription (German et al.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 60.540kDa inclusive of tags
• Protein Length: 313 amino acids
• AA Sequence: MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDY GGYHVAAAAAAAANLDSAQSPGPSWPAAYGAPLREDWNGY APGGAAAAANAVAHGPNGGSPAAAMGYSSPADYHPHHHPH HHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGG QRRNLCEWMRKPAQQSLGSQVKTRTKDKYRVVYTDHQRLE LEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAK ERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPE PLSPVSSLQASVSGSVPGVLGPTGGVLNPTVTQ
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: CDX2 caudal type homeobox 2 [ Homo sapiens ]
• Official Symbol: CDX2
• Synonyms: CDX2; caudal type homeobox 2; caudal type homeo box transcription factor 2 , CDX3; homeobox protein CDX-2
• Gene ID: 1045
• mRNA Refseq: NM_001265
• Protein Refseq: NP_001256
• MIM: 600297
• UniProt ID: Q99626