Recombinant Full Length Human COL8A2 Protein, GST-tagged

• Cat.No.: COL8A2-2180HF
• Product Overview: Human COL8A2 full-length ORF ( AAH96296.1, 1 a.a. - 427 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 68.9 kDa
• Protein Length: 427 amino acids
• AA Sequence: MLGTLTPLSSLLLLLLVLVLGCGPR ASSGGGAGGAAGYAPVKYIQPMQKG PVGPPFREGKGQYLEMPLPLLPMDL KGEPGPPGKPGPRGPPGPPGFPGKP GMGKPGLHGQPGPAGPPGFSRMGKA GPPGLPGKVGPPGQPGLRGEPGIRG DQGLRGPPGPPGLPGPSGITIPGKP GAQGVPGPPGFQGEPGPQGEPGPPG DRGLKGDNGVGQPGLPGAPGQGGAP GPPGLPGPAGLGKPGLDGLPGAPGD KGESGPPGAFDETGIAGLHLPNGGV EGAVLGKGGKPQFGLGELSAHATPA FTAVLTSPFPASGMPVKFDRTLYNG HSGYNPATGIFTCPVGGVYYFAYHV HVKGTNVWVALYKNNVPATYTYDEY KKGYLDQASGGAVLQLRPNDQVWVQ MPSDQANGLYSTEYIHSSFSGFLLC PT
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: COL8A2 collagen, type VIII, alpha 2 [ Homo sapiens ]
• Official Symbol: COL8A2
• Synonyms: COL8A2; collagen, type VIII, alpha 2; FECD; collagen alpha-2(VIII) chain; PPCD; PPCD2; endothelial collagen; collagen VIII, alpha-2 polypeptide; dJ665N4.1 (collagen type VIII alpha 2); FECD1; FLJ00201; MGC116970; MGC116972
• Gene ID: 1296
• mRNA Refseq: NM_005202
• Protein Refseq: NP_005193
• MIM: 120252
• UniProt ID: P25067