Recombinant Full Length Human CXCL10 Protein, C-Flag-tagged

• Cat.No.: CXCL10-583HFL
• Product Overview: Recombinant Full Length Human CXCL10 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 8.6 kDa
• AA Sequence: MNQTAILICCLIFLTLSGIQGVPLS RTVRCTCISISNQPVNPRSLEKLEI IPASQFCPRVEIIATMKKKGEKRCL NPESKAIKNLLKAVSKERSKRSPTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway

Gene Information

• Gene Name: CXCL10 C-X-C motif chemokine ligand 10 [ Homo sapiens (human) ]
• Official Symbol: CXCL10
• Synonyms: C7; IFI10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10
• Gene ID: 3627
• mRNA Refseq: NM_001565.4
• Protein Refseq: NP_001556.2
• MIM: 147310
• UniProt ID: P02778