Recombinant Full Length Human DAZL Protein, GST-tagged
Cat.No. : | DAZL-2546HF |
Product Overview : | Human DAZL full-length ORF ( AAH27595, 1 a.a. - 295 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 58.19 kDa |
Protein Length : | 295 amino acids |
AA Sequence : | MSTANPETPNSTISREASTQSSSAA TSQGYILPEGKIMPNTVFVGGIDVR MDETEIRSFFARYGSVKEVKIITDR TGVSKGYGFVSFFNDVDVQKIVESQ INFHGKKLKLGPAIRKQNLCAYHVQ PRPLVFNHPPPPQFQNVWTNPNTET YMQPTTTMNPITQYVQAYPTYPNSP VQVITGYQLPVYNYQMPPQWPVGEQ RSYVVPPAYSAVNYHCNEVDPGAEV VPNECSVHEATPPSGNGPQKKSVDR SIQTVVSCLFNPENRLRNSVVTQDD YFKDKRVHHFRRSRAMLKSV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | DAZL deleted in azoospermia-like [ Homo sapiens ] |
Official Symbol : | DAZL |
Synonyms : | DAZL; deleted in azoospermia-like; DAZLA; DAZH; DAZL1; MGC26406; SPGYLA; DAZ homolog; DAZ-like autosomal; SPGY-like-autosomal; deleted in azoospermia-like 1; germline specific RNA binding protein; spermatogenesis gene on the Y-like autosomal; |
Gene ID : | 1618 |
mRNA Refseq : | NM_001190811 |
Protein Refseq : | NP_001177740 |
MIM : | 601486 |
UniProt ID : | Q92904 |
Products Types
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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