Recombinant Full Length Human DDC Protein, C-Flag-tagged
Cat.No. : | DDC-1314HFL |
Product Overview : | Recombinant Full Length Human DDC Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 53.7 kDa |
AA Sequence : | MNASEFRRRGKEMVDYVANYMEGIE GRQVYPDVEPGYLRPLIPAAAPQEP DTFEDIINDVEKIIMPGVTH WHSPYFFAYFPTASSYPAMLADMLC GAIGCIGFSWAASPACTELETVMMD WLGKMLELPKAFLNEKAGEG GGVIQGSASEATLVALLAARTKVIH RLQAASPELTQAAIMEKLVAYSSDQ AHSSVERAGLIGGVKLKAIP SDGNFAMRASALQEALERDKAAGLI PFFMVATLGTTTCCSFDNLLEVGPI CNKEDIWLHVDAAYAGSAFI CPEFRHLLNGVEFADSFNFNPHKWL LVNFDCSAMWVKKRTDLTGAFRLDP TYLKHSHQDSGLITDYRHWQ IPLGRRFRSLKMWFVFRMYGVKGLQ AYIRKHVQLSHEFESLVRQDPRFEI CVEVILGLVCFRLKGSNKVN EALLQRINSAKKIHLVPCHLRDKFV LRFAICSRTVESAHVQRAWEHIKEL AADVLRAERETRTRPLEQKLISEED LAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Tryptophan metabolism, Tyrosine metabolism |
Gene Name : | DDC dopa decarboxylase [ Homo sapiens (human) ] |
Official Symbol : | DDC |
Synonyms : | AADC |
Gene ID : | 1644 |
mRNA Refseq : | NM_000790.4 |
Protein Refseq : | NP_000781.2 |
MIM : | 107930 |
UniProt ID : | P20711 |
Products Types
◆ Recombinant Protein | ||
Ddc-2490M | Recombinant Mouse Ddc Protein, Myc/DDK-tagged | +Inquiry |
DDC-284H | Active Recombinant Human DDC protein(Met1-Glu480), His-tagged | +Inquiry |
DDC-491H | Recombinant Human DDC Protein, His-tagged | +Inquiry |
DDC-731H | Recombinant Human DDC Protein, His (Fc)-Avi-tagged | +Inquiry |
DDC-0240H | Recombinant Human DDC Protein (M1-E480), Tag Free | +Inquiry |
◆ Lysates | ||
DDC-724HCL | Recombinant Human DDC cell lysate | +Inquiry |
DDC-513MCL | Recombinant Mouse DDC cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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