Recombinant Full Length Human DES Protein, GST-tagged

• Cat.No.: DES-2476HF
• Product Overview: Human DES full-length ORF (AAH32116.1, 1 a.a. - 470 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 79.9 kDa
• Protein Length: 470 amino acids
• AA Sequence: MSQAYSSSQRVSSYRRTFGGAPGFP LGSPLSSPVFPRAGFGSKGSSSSVT SRVYQVSRTSGGAGGLGSLRASRLG TTRTPSSYGAGELLDFSLADAVNQE FLTTRTNEKVELQELNDRFANYIEK VRFLEQQNAALAAEVNRLKGREPTR VAELYEEELRELRRQVEVLTNQRAR VDVERDNLLDDLQRLKAKLQEEIQL KEEAENNLAAFRADVDAATLARIDL ERRIESLNEEIAFLKKVHEEEIREL QAQLQEQQVQVEMDMSKPDLTAALR DIRAQYETIAAKNISEAEEWYKSKV SDLTQAANKNNDALRQAKQEMMEYR HQIQSYTCEIDALKGTNDSLMRQMR ELEDRFASEASGYQDNIARLEEEIR HLKDEMARHLREYQDLLNVKMALDV EIATYRKLLEGEESRINLPIQTYSA LNFRETSPEQRGSEVHTKKTVMIKT IETRDGEVVSEATQQQHEVL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DES desmin [ Homo sapiens ]
• Official Symbol: DES
• Synonyms: DES; desmin; CMD1I; CSM1; CSM2; intermediate filament protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793
• Gene ID: 1674
• mRNA Refseq: NM_001927
• Protein Refseq: NP_001918
• MIM: 125660
• UniProt ID: P17661