Recombinant Full Length Human DHCR24 Protein, C-Flag-tagged
Cat.No. : | DHCR24-2126HFL |
Product Overview : | Recombinant Full Length Human DHCR24 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 57.6 kDa |
AA Sequence : | MEPAVSLAVCALLFLLWVRLKGLEF VLIHQRWVFVCLFLLPLSLIFDIYY YVRAWVVFKLSSAPRLHEQR VRDIQKQVREWKEQGSKTFMCTGRP GWLTVSLRVGKYKKTHKNIMINLMD ILEVDTKKQIVRVEPLVTMG QVTALLTSIGWTLPVLPELDDLTVG GLIMGTGIESSSHKYGLFQHICTAY ELVLADGSFVRCTPSENSDL FYAVPWSCGTLGFLVAAEIRIIPAK KYVKLRFEPVRGLEAICAKFTHESQ RQENHFVEGLLYSLDEAVIM TGVMTDEAEPSKLNSIGNYYKPWFF KHVENYLKTNREGLEYIPLRHYYHR HTRSIFWELQDIIPFGNNPI FRYLFGWMVPPKISLLKLTQGETLR KLYEQHHVVQDMLVPMKCLQQALHT FQNDIHVYPIWLCPFILPSQ PGLVHPKGNEAELYIDIGAYGEPRV KHFEARSCMRQLEKFVRSVHGFQML YADCYMNREEFWEMFDGSLY HKLREKLGCQDAFPEVYDKICKAAR H TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, Stem cell - Pluripotency, Transmembrane |
Protein Pathways : | Metabolic pathways, Steroid biosynthesis |
Gene Name : | DHCR24 24-dehydrocholesterol reductase [ Homo sapiens (human) ] |
Official Symbol : | DHCR24 |
Synonyms : | DCE; SELADIN1; Nbla03646; seladin-1 |
Gene ID : | 1718 |
mRNA Refseq : | NM_014762.4 |
Protein Refseq : | NP_055577.1 |
MIM : | 606418 |
UniProt ID : | Q15392 |
Products Types
◆ Recombinant Protein | ||
Dhcr24-2542M | Recombinant Mouse Dhcr24 Protein, Myc/DDK-tagged | +Inquiry |
DHCR24-754H | Recombinant Human DHCR24 Protein, His (Fc)-Avi-tagged | +Inquiry |
DHCR24-208C | Recombinant Cynomolgus Monkey DHCR24 Protein, His (Fc)-Avi-tagged | +Inquiry |
DHCR24-2944C | Recombinant Chicken DHCR24 | +Inquiry |
DHCR24-106H | Recombinant Human DHCR24 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
DHCR24-6950HCL | Recombinant Human DHCR24 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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