Recombinant Full Length Human DIS3L2 Protein, C-Flag-tagged

• Cat.No.: DIS3L2-1725HFL
• Product Overview: Recombinant Full Length Human DIS3L2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 99.1 kDa
• AA Sequence: MSHPDYRMNLRPLGTPRGVSAVAGP HDIGASPGDKKSKNRSTRGKKKSIF ETYMSKEDVSEGLKRGTLIQ GVLRINPKKFHEAFIPSPDGDRDIF IDGVVARNRALNGDLVVVKLLPEEH WKVVKPESNDKETEAAYESD IPEELCGHHLPQQSLKSYNDSPDVI VEAQFDGSDSEDGHGITQNVLVDGV KKLSVCVSEKGREDGDAPVT KDETTCISQDTRALSEKSLQRSAKV VYILEKKHSRAATGFLKLLADKNSE LFRKYALFSPSDHRVPRIYV PLKDCPQDFVARPKDYANTLFICRI VDWKEDCNFALGQLAKSLGQAGEIE PETEGILTEYGVDFSDFSSE VLECLPQGLPWTIPPEEFSKRRDLR KDCIFTIDPSTARDLDDALSCKPLA DGNFKVGVHIADVSYFVPEG SDLDKVAAERATSVYLVQKVVPMLP RLLCEELCSLNPMSDKLTFSVIWTL TPEGKILDEWFGRTIIRSCT KLSYEHAQSMIESPTEKIPAKELPP ISPEHSSEEVHQAVLNLHGIAKQLR QQRFVDGALRLDQLKLAFTL DHETGLPQGCHIYEYRESNKLVEEF MLLANMAVAHKIHRAFPEQALLRRH PPPQTRMLSDLVEFCDQMGL PVDFSSAGALNKSLTQTFGDDKYSL ARKEVLTNMCSRPMQMALYFCSGLL QDPAQFRHYALNVPLYTHFT SPIRRFADVLVHRLLAAALGYRERL DMAPDTLQKQADHCNDRRMASKRVQ ELSTSLFFAVLVKESGPLES EAMVMGILKQAFDVLVLRYGVQKRI YCNALALRSHHFQKVGKKPELTLVW EPEDMEQEPAQQVITIFSLV
  EVVLQAESTALKYSAILKRPGTQGH LGPEKEEEESDGEPEDSSTSTRTRP LEQKLISEEDLAANDILDYKDDDDK V
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: DIS3L2 DIS3 like 3'-5' exoribonuclease 2 [ Homo sapiens (human) ]
• Official Symbol: DIS3L2
• Synonyms: FAM6A; PRLMNS; hDIS3L2
• Gene ID: 129563
• mRNA Refseq: NM_152383.5
• Protein Refseq: NP_689596.4
• MIM: 614184
• UniProt ID: Q8IYB7