Recombinant Full Length Human DPYD Protein, GST-tagged
Cat.No. : | DPYD-4165HF |
Product Overview : | Human DPYD full-length ORF ( AAH08379, 1 a.a. - 173 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 44.66 kDa |
Protein Length : | 173 amino acids |
AA Sequence : | MAPVLSKDSADIESILALNPRTQTH ATLCSTSAKKLDKKHWKRNPDKNCF NCEKLENNFDDIKHTTLGERGALRE AMRCLKCADAPCQKSCPTNLDIKSF ITSIANKNYYGAAKMIFSDNPLGLT CGMVCPTSDLCVGGCNLYATEEGPI NIGGLQQFATETLILAFSLMNHL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | DPYD dihydropyrimidine dehydrogenase [ Homo sapiens ] |
Official Symbol : | DPYD |
Synonyms : | DPYD; dihydropyrimidine dehydrogenase; dihydropyrimidine dehydrogenase [NADP(+)]; DPD; dihydrouracil dehydrogenase; dihydrothymine dehydrogenase; DHP; DHPDHASE; MGC70799; MGC132008; |
Gene ID : | 1806 |
mRNA Refseq : | NM_000110 |
Protein Refseq : | NP_000101 |
MIM : | 612779 |
UniProt ID : | Q12882 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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