Recombinant Full Length Human DSE Protein, GST-tagged
Cat.No. : | DSE-4253HF |
Product Overview : | Human DSE full-length ORF ( NP_037484.1, 1 a.a. - 958 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 136.2 kDa |
Protein Length : | 958 amino acids |
AA Sequence : | MRTHTRGAPSVFFIYLLCFVSAYIT DENPEVMIPFTNANYDSHPMLYFSR AEVAELQLRAASSHEHIAARLTEAV HTMLSSPLEYLPPWDPKDYSARWNE IFGNNLGALAMFCVLYPENIEARDM AKDYMERMAAQPSWLVKDAPWDEVP LAHSLVGFATAYDFLYNYLSKTQQE KFLEVIANASGYMYETSYRRGWGFQ YLHNHQPTNCMALLTGSLVLMNQGY LQEAYLWTKQVLTIMEKSLVLLREV TDGSLYEGVAYGSYTTRSLFQYMFL VQRHFNINHFGHPWLKQHFAFMYRT ILPGFQRTVAIADSNYNWFYGPESQ LVFLDKFVMRNGSGNWLADQIRRNR VVEGPGTPSKGQRWCTLHTEFLWYD GSLKSVPPPDFGTPTLHYFEDWGVV TYGSALPAEINRSFLSFKSGKLGGR AIYDIVHRNKYKDWIKGWRNFNAGH EHPDQNSFTFAPNGVPFITEALYGP KYTFFNNVLMFSPAVSKSCFSPWVG QVTEDCSSKWSKYKHDLAASCQGRV VAAEEKNGVVFIRGEGVGAYNPQLN LKNVQRNLILLHPQLLLLVDQIHLG EESPLETAASFFHNVDVPFEETVVD GVHGAFIRQRDGLYKMYWMDDTGYS EKATFASVTYPRGYPYNGTNYVNVT MHLRSPITRAAYLFIGPSIDVQSFT VHGDSQQLDVFIATSKHAYATYLWT GEATGQSAFAQVIADRHKILFDRNS AIKSSIVPEVKDYAAIVEQNLQHFK PVFQLLEKQILSRVRNTASFRKTAE RLLRFSDKRQTEEAIDRIFAISQQQ QQQSKSKKNRRAGKRYKFVDAVPDI FAQIEVNEKKIRQKAQILAQKELPI DEDEEMKDLLDFADVTYEKHKNGGL IKGRFGQARMVTTTHSRAPSLSASY TRLFLILNIAIFFVMLAMQLTYFQR AQSLHGQRCLYAVLLIDSCILLWLY SSCSQSQC |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | DSE dermatan sulfate epimerase [ Homo sapiens ] |
Official Symbol : | DSE |
Synonyms : | DSE; dermatan sulfate epimerase; SART2, squamous cell carcinoma antigen recognized by T cells 2; dermatan-sulfate epimerase; DSEPI; DS epimerase; chondroitin-glucuronate 5-epimerase; squamous cell carcinoma antigen recognized by T cells 2; squamous cell carcinoma antigen recognized by T-cells 2; DSEP; SART2; SART-2; |
Gene ID : | 29940 |
mRNA Refseq : | NM_001080976 |
Protein Refseq : | NP_001074445 |
MIM : | 605942 |
UniProt ID : | Q9UL01 |
Products Types
◆ Recombinant Protein | ||
DSE-1387H | Recombinant Human DSE Protein, His-tagged | +Inquiry |
DSE-2888H | Recombinant Human DSE Protein, GST-tagged | +Inquiry |
DSE-2536M | Recombinant Mouse DSE Protein, His (Fc)-Avi-tagged | +Inquiry |
DSE-3319Z | Recombinant Zebrafish DSE | +Inquiry |
DSE-4837M | Recombinant Mouse DSE Protein | +Inquiry |
◆ Lysates | ||
DSE-511HCL | Recombinant Human DSE cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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