Recombinant Human DSE Protein, His-tagged
Cat.No. : | DSE-1387H |
Product Overview : | Recombinant Human DSE Protein (Tyr23-His284) with N-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. |
Source : | E. coli |
Species : | Human |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 34.0 kDa |
Protein length : | Tyr23-His284 |
Purity : | > 97% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in PBS or others. |
Gene Name : | DSE dermatan sulfate epimerase [ Homo sapiens (human) ] |
Official Symbol : | DSE |
Synonyms : | DSE; dermatan sulfate epimerase; SART2, squamous cell carcinoma antigen recognized by T cells 2; dermatan-sulfate epimerase; DSEPI; DS epimerase; chondroitin-glucuronate 5-epimerase; squamous cell carcinoma antigen recognized by T cells 2; squamous cell carcinoma antigen recognized by T-cells 2; DSEP; SART2; SART-2; |
Gene ID : | 29940 |
mRNA Refseq : | NM_001080976 |
Protein Refseq : | NP_001074445 |
MIM : | 605942 |
UniProt ID : | Q9UL01 |
Products Types
◆ Recombinant Protein | ||
DSE-2888H | Recombinant Human DSE Protein, GST-tagged | +Inquiry |
DSE-2536M | Recombinant Mouse DSE Protein, His (Fc)-Avi-tagged | +Inquiry |
DSE-4837M | Recombinant Mouse DSE Protein | +Inquiry |
DSE-3319Z | Recombinant Zebrafish DSE | +Inquiry |
◆ Lysates | ||
DSE-511HCL | Recombinant Human DSE cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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