Recombinant Full Length Human ECM1 Protein, C-Flag-tagged

• Cat.No.: ECM1-1621HFL
• Product Overview: Recombinant Full Length Human ECM1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 58.8 kDa
• AA Sequence: MGTTARAALVLTYLAVASAASEGGF TATGQRQLRPEHFQEVGYAAPPSPP LSRSLPMDHPDSSQHGPPFE GQSQVQPPPSQEATPLQQEKLLPAQ LPAEKEVGPPLPQEAVPLQKELPSL QHPNEQKEGMPAPFGDQSHP EPESWNAAQHCQQDRSQGGWGHRLD GFPPGRPSPDNLNQICLPNRQHVVY GPWNLPQSSYSHLTRQGETL NFLEIGYSRCCHCRSHTNRLECAKL VWEEAMSRFCEAEFSVKTRPHWCCT RQGEARFSCFQEEAPQPHYQ LRACPSHQPDISSGLELPFPPGVPT LDNIKNICHLRRFRSVPRNLPATDP LQRELLALIQLEREFQRCCR QGNNHTCTWKAWEDTLDKYCDREYA VKTHHHLCCRHPPSPTRDECFARRA PYPNYDRDILTIDISRVTPN LMGHLCGNQRVLTKHKHIPGLIHNM TARCCDLPFPEQACCAEEEKLTFIN DLCGPRRNIWRDPALCCYLS
  PGDEQVNCFNINYLRNVALVSGDTE NAKGQGEQGSTGGTNISSTSEPKEE TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein, Transmembrane

Gene Information

• Gene Name: ECM1 extracellular matrix protein 1 [ Homo sapiens (human) ]
• Official Symbol: ECM1
• Synonyms: URBWD
• Gene ID: 1893
• mRNA Refseq: NM_004425.4
• Protein Refseq: NP_004416.2
• MIM: 602201
• UniProt ID: Q16610