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Recombinant Full Length Human EFNA1 Protein, GST-tagged

Cat.No. : EFNA1-4215HF
Product Overview : Human EFNA1 full-length ORF ( NP_004419.2, 1 a.a. - 205 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008]
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 50.2 kDa
Protein Length : 205 amino acids
AA Sequence : MEFLWAPLLGLCCSLAAADRHTVFW NSSNPKFRNEDYTIHVQLNDYVDII CPHYEDHSVADAAMEQYILYLVEHE EYQLCQPQSKDQVRWQCNRPSAKHG PEKLSEKFQRFTPFTLGKEFKEGHS YYYISKPIHQHEDRCLRLKVTVSGK ITHSPQAHDNPQEKRLAADDPEVRV LHSIGHSAAPRLFPLAWTVLLLPLL LLQTP
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : EFNA1 ephrin-A1 [ Homo sapiens ]
Official Symbol : EFNA1
Synonyms : EFNA1; ephrin-A1; EPLG1, TNFAIP4; ECKLG; LERK1; TNF alpha-induced protein 4; ligand of eph-related kinase 1; immediate early response protein B61; eph-related receptor tyrosine kinase ligand 1; tumor necrosis factor alpha-induced protein 4; tumor necrosis factor, alpha-induced protein 4; B61; EFL1; EPLG1; LERK-1; TNFAIP4;
Gene ID : 1942
mRNA Refseq : NM_004428
Protein Refseq : NP_004419
MIM : 191164
UniProt ID : P20827

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can EFNA1 be a target for therapeutic interventions in cancer treatment? 05/06/2021

Yes, EFNA1 is being investigated as a potential therapeutic target in cancer treatment, aiming to develop drugs that modulate its activity.

Are there diagnostic applications for EFNA1 in cancer detection? 01/15/2021

Researchers are exploring the use of EFNA1 as a biomarker for cancer detection, with studies suggesting its potential as a diagnostic tool.

How does EFNA1 interact with the Eph receptors, and what is the significance of this interaction? 04/16/2019

EFNA1 binds to Eph receptors, initiating cell signaling pathways that regulate various cellular processes, making this interaction crucial for normal physiological functions.

How does EFNA1 impact cancer research and treatment? 02/02/2018

EFNA1 is implicated in cancer progression, influencing cell migration and invasion. Understanding its role can potentially lead to targeted therapies for certain cancers.

Are there any neurological disorders associated with EFNA1 dysregulation? 10/26/2016

Dysregulation of EFNA1 has been linked to certain neurological disorders, including Alzheimer's disease and neurodevelopmental disorders.

Customer Reviews (3)

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Reviews
08/15/2019

    Their prompt assistance and willingness to go above and beyond to ensure my success have been immensely valuable.

    04/04/2019

      Its purity, stability, and consistency are unparalleled, ensuring reliable and reproducible results in my research.

      11/22/2016

        This protein has proven to be an invaluable asset in my experiments, enabling accurate and precise measurements with exceptional sensitivity.

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