Recombinant Full Length Human EFNA1 Protein, GST-tagged
Cat.No. : | EFNA1-4215HF |
Product Overview : | Human EFNA1 full-length ORF ( NP_004419.2, 1 a.a. - 205 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 50.2 kDa |
Protein Length : | 205 amino acids |
AA Sequence : | MEFLWAPLLGLCCSLAAADRHTVFW NSSNPKFRNEDYTIHVQLNDYVDII CPHYEDHSVADAAMEQYILYLVEHE EYQLCQPQSKDQVRWQCNRPSAKHG PEKLSEKFQRFTPFTLGKEFKEGHS YYYISKPIHQHEDRCLRLKVTVSGK ITHSPQAHDNPQEKRLAADDPEVRV LHSIGHSAAPRLFPLAWTVLLLPLL LLQTP |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | EFNA1 ephrin-A1 [ Homo sapiens ] |
Official Symbol : | EFNA1 |
Synonyms : | EFNA1; ephrin-A1; EPLG1, TNFAIP4; ECKLG; LERK1; TNF alpha-induced protein 4; ligand of eph-related kinase 1; immediate early response protein B61; eph-related receptor tyrosine kinase ligand 1; tumor necrosis factor alpha-induced protein 4; tumor necrosis factor, alpha-induced protein 4; B61; EFL1; EPLG1; LERK-1; TNFAIP4; |
Gene ID : | 1942 |
mRNA Refseq : | NM_004428 |
Protein Refseq : | NP_004419 |
MIM : | 191164 |
UniProt ID : | P20827 |
Products Types
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EFNA1-3096H | Recombinant Human EFNA1 Protein, GST-tagged | +Inquiry |
Efna1-159M | Recombinant Mouse Efna1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Efna1-2753M | Recombinant Mouse Efna1 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
EFNA1-2594HCL | Recombinant Human EFNA1 cell lysate | +Inquiry |
EFNA1-1514RCL | Recombinant Rat EFNA1 cell lysate | +Inquiry |
EFNA1-2177MCL | Recombinant Mouse EFNA1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, EFNA1 is being investigated as a potential therapeutic target in cancer treatment, aiming to develop drugs that modulate its activity.
Researchers are exploring the use of EFNA1 as a biomarker for cancer detection, with studies suggesting its potential as a diagnostic tool.
EFNA1 binds to Eph receptors, initiating cell signaling pathways that regulate various cellular processes, making this interaction crucial for normal physiological functions.
EFNA1 is implicated in cancer progression, influencing cell migration and invasion. Understanding its role can potentially lead to targeted therapies for certain cancers.
Dysregulation of EFNA1 has been linked to certain neurological disorders, including Alzheimer's disease and neurodevelopmental disorders.
Customer Reviews (3)
Write a reviewTheir prompt assistance and willingness to go above and beyond to ensure my success have been immensely valuable.
Its purity, stability, and consistency are unparalleled, ensuring reliable and reproducible results in my research.
This protein has proven to be an invaluable asset in my experiments, enabling accurate and precise measurements with exceptional sensitivity.
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