Recombinant Full Length Human EIF3F Protein, C-Flag-tagged

• Cat.No.: EIF3F-2049HFL
• Product Overview: Recombinant Full Length Human EIF3F Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables deubiquitinase activity and identical protein binding activity. Contributes to translation initiation factor activity. Involved in IRES-dependent viral translational initiation; protein deubiquitination; and translational initiation. Located in membrane. Part of eukaryotic translation initiation factor 3 complex. Implicated in autosomal recessive non-syndromic intellectual disability.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 37.4 kDa
• AA Sequence: MATPAVPVSAPPATPTPVPAAAPAS VPAPTPAPAAAPVPAAAPASSSDPA AAAAATAAPGQTPASAQAPA QTPAPALPGPALPGPFPGGRVVRLH PVILASIVDSYERRNEGAARVIGTL LGTVDKHSVEVTNCFSVPHN ESEDEVAVDMEFAKNMYELHKKVSP NELILGWYATGHDITEHSVLIHEYY SREAPNPIHLTVDTSLQNGR MSIKAYVSTLMGVPGRTMGVMFTPL TVKYAYYDTERIGVDLIMKTCFSPN RVIGLSSDLQQVGGASARIQ DALSTVLQYAEDVLSGKVSADNTVG RFLMSLVNQVPKIVPDDFETMLNSN INDLLMVTYLANLTQSQIAL NEKLVNL SGPTRTRRLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: EIF3F eukaryotic translation initiation factor 3 subunit F [ Homo sapiens (human) ]
• Official Symbol: EIF3F
• Synonyms: MRT67; EIF3S5; eIF3-p47
• Gene ID: 8665
• mRNA Refseq: NM_003754.3
• Protein Refseq: NP_003745.1
• MIM: 603914
• UniProt ID: O00303