Recombinant Full Length Human EZH1 Protein, C-Flag-tagged

• Cat.No.: EZH1-1661HFL
• Product Overview: Recombinant Full Length Human EZH1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 85.1 kDa
• AA Sequence: MEIPNPPTSKCITYWKRKVKSEYMR LRQLKRLQANMGAKALYVANFAKVQ EKTQILNEEWKKLRVQPVQS MKPVSGHPFLKKCTIESIFPGFASQ HMLMRSLNTVALVPIMYSWSPLQQN FMVEDETVLCNIPYMGDEVK EEDETFIEELINNYDGKVHGEEEMI PGSVLISDAVFLELVDALNQYSDEE EEGHNDTSDGKQDDSKEDLP VTRKRKRHAIEGNKKSSKKQFPNDM IFSAIASMFPENGVPDDMKERYREL TEMSDPNALPPQCTPNIDGP NAKSVQREQSLHSFHTLFCRRCFKY DCFLHPFHATPNVYKRKNKEIKIEP EPCGTDCFLLLEGAKEYAML HNPRSKCSGRRRRRHHIVSASCSNA SASAVAETKEGDSDRDTGNDWASSS SEANSRCQTPTKQKASPAPP QLCVVEAPSEPVEWTGAEESLFRVF HGTYFNNFCSIARLLGTKTCKQVFQ FAVKESLILKLPTDELMNPS QKKKRKHRLWAAHCRKIQLKKDNSS TQVYNYQPCDHPDRPCDSTCPCIMT QNFCEKFCQCNPDCQNRFPG CRCKTQCNTKQCPCYLAVRECDPDL CLTCGASEHWDCKVVSCKNCSIQRG LKKHLLLAPSDVAGWGTFIK ESVQKNEFISEYCGELISQDEADRR GKVYDKYMSSFLFNLNNDFVVDATR KGNKIRFANHSVNPNCYAKV
  VMVNGDHRIGIFAKRAIQAGEELFF DYRYSQADALKYVGIERETDVLTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transcription Factors

Gene Information

• Gene Name: EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit [ Homo sapiens (human) ]
• Official Symbol: EZH1
• Synonyms: KMT6B
• Gene ID: 2145
• mRNA Refseq: NM_001991.5
• Protein Refseq: NP_001982.2
• MIM: 601674
• UniProt ID: Q92800