Recombinant Full Length Human GABBR2 Protein, GST-tagged

• Cat.No.: GABBR2-5178HF
• Product Overview: Human GABBR2 full-length ORF ( AAH35071.2, 1 a.a. - 883 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: B-type receptors for the neurotransmitter GABA (gamma-aminobutyric acid) inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters and the activity of ion channels and adenylyl cyclase. See GABBR1 (MIM 603540) for additional background information on GABA-B receptors.[supplied by OMIM
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 126.3 kDa
• Protein length: 883 amino acids
• AA Sequence: MGLMPLTKEVAKGSIGRGVLPAVEL AIEQIRNESLLRPYFLDLRLYDTEC DNAKGLKAFYDAIKYGPNHLMVFGG VCPSVTSIIAESLQGWNLVQLSFAA TTPVLADKKKYPYFFRTVPSDNAVN PAILKLLKHYQWKRVGTLTQDVQRF SEVRNDLTGVLYGEDIEISDTESFS NDPCTSVKKLKGNDVRIILGQFDQN MAAKVFCCAYEENMYGSKYQWIIPG WYEPSWWEQVHTEANSSRCLRKNLL AAMEGYIGVDFEPLSSKQIKTISGK TPQQYEREYNNKRSGVGPSKFHGYA YDGIWVIAKTLQRAMETLHASSRHQ RIQDFNYTDHTLGRIILNAMNETNF FGVTGQVVFRNGERMGTIKFTQFQD SREVKVGEYNAVADTLEIINDTIRF QGSEPPKDKTIILEQLRKISLPLYS ILSALTILGMIMASAFLFFNIKNRN QKLIKMSSPYMNNLIILGGMLSYAS IFLFGLDGSFVSEKTFETLCTVRTW ILTVGYTTAFGAMFAKTWRVHAIFK NVKMKKKIIKDQKLLVIVGGMLLID LCILICWQAVDPLRRTVEKYSMEPD PAGRDISIRPLLEHCENTHMTIWLG IVYAYKGLLMLFGCFLAWETRNVSI PALNDSKYIGMSVYNVGIMCIIGAA VSFLTRDQPNVQFCIVALVIIFCST ITLCLVFVPKLITLRTNPDAATQNR RFQFTQNQKKEDSKTSTSVTSVNQA STSRLEGLQSENHHLRMKITELDKD LEEVTMQLQDTPEKTTYIKQNHYQE LNDILNLGNFTESTDGGKAILKNHL DQNPQLQWNTTEPSRTCKDPIEDIN SPEHIQRRLSLQLPILHHAYLPSIG GVDASCVSPCVSPTASPRHRHVPPS FRVMVSGL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 [ Homo sapiens ]
• Official Symbol: GABBR2
• Synonyms: GABBR2; gamma-aminobutyric acid (GABA) B receptor, 2; G protein coupled receptor 51, GPR51; gamma-aminobutyric acid type B receptor subunit 2; GABABR2; GPRC3B; HG20; gb2; GABA-BR2; GABA-B-R2; GABA-B receptor 2; GABA-B receptor, R2 subunit; G protein-coupled receptor 51; G-protein coupled receptor 51; gamma-aminobutyric acid B receptor 2; GPR51; HRIHFB2099; FLJ36928
• Gene ID: 9568
• mRNA Refseq: NM_005458
• Protein Refseq: NP_005449
• MIM: 607340
• UniProt ID: O75899