Recombinant Full Length Human GBP5 Protein, C-Flag-tagged

• Cat.No.: GBP5-1159HFL
• Product Overview: Recombinant Full Length Human GBP5 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene belongs to the TRAFAC class dynamin-like GTPase superfamily. The encoded protein acts as an activator of NLRP3 inflammasome assembly and has a role in innate immunity and inflammation. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 66.4 kDa
• AA Sequence: MALEIHMSDPMCLIENFNEQLKVNQ EALEILSAITQPVVVVAIVGLYRTG KSYLMNKLAGKNKGFSVAST VQSHTKGIWIWCVPHPNWPNHTLVL LDTEGLGDVEKADNKNDIQIFALAL LLSSTFVYNTVNKIDQGAID LLHNVTELTDLLKARNSPDLDRVED PADSASFFPDLVWTLRDFCLGLEID GQLVTPDEYLENSLRPKQGS DQRVQNFNLPRLCIQKFFPKKKCFI FDLPAHQKKLAQLETLPDDELEPEF VQQVTEFCSYIFSHSMTKTL PGGIMVNGSRLKNLVLTYVNAISSG DLPCIENAVLALAQRENSAAVQKAI AHYDQQMGQKVQLPMETLQE LLDLHRTSEREAIEVFMKNSFKDVD QSFQKELETLLDAKQNDICKRNLEA SSDYCSALLKDIFGPLEEAV KQGIYSKPGGHNLFIQKTEELKAKY YREPRKGIQAEEVLQKYLKSKESVS HAILQTDQALTETEKKKKEA QVKAEAEKAEAQRLAAIQRQNEQMM QERERLHQEQVRQMEIAKQNWLAEQ QKMQEQQMQEQAAQLSTTFQ
  AQNRSLLSELQHAQRTVNNDDPCVL LTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: GBP5 guanylate binding protein 5 [ Homo sapiens (human) ]
• Official Symbol: GBP5
• Synonyms: GBP-5
• Gene ID: 115362
• mRNA Refseq: NM_001134486.4
• Protein Refseq: NP_001127958.1
• MIM: 611467
• UniProt ID: Q96PP8