Recombinant Full Length Human GCA Protein, GST-tagged
Cat.No. : | GCA-5164HF |
Product Overview : | Human GCA full-length ORF ( AAH05214, 1 a.a. - 217 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation. [provided by RefSeq |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 49.61 kDa |
Protein length : | 217 amino acids |
AA Sequence : | MAYPGYGGGFGNFSIQVPGMQMGQP VPETGPAILLDGYSGPAYSDTYSSA GDSVYTYFSAVAGQDGEVDAEELQR CLTQSGINGTYSPFSLETCRIMIAM LDRDHTGKMGFNAFKELWAALNAWK ENFMTVDQDGSGTVEHHELRQAIGL MGYRLSPQTLTTIVKRYSKNGRIFF DDYVACCVKLRALTDFFRKRDHLQQ GSANFIYDDFLQGTMAI |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GCA grancalcin, EF-hand calcium binding protein [ Homo sapiens ] |
Official Symbol : | GCA |
Synonyms : | GCA; grancalcin, EF-hand calcium binding protein; grancalcin, EF hand calcium binding protein; grancalcin; GCL; grancalcin, penta-EF-hand protein; grancalcin, EF-hand calcium-binding protein; |
Gene ID : | 25801 |
mRNA Refseq : | NM_012198 |
Protein Refseq : | NP_036330 |
MIM : | 607030 |
UniProt ID : | P28676 |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewIn ELISA assays, it has consistently exhibited exceptional reliability and accuracy, providing precise and reproducible results.
Their prompt and knowledgeable guidance has been instrumental in effectively addressing my queries and optimizing the utilization of the GCA protein in my studies.
The GCA protein comes highly recommended for its outstanding performance in various experimental applications.
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