Recombinant Full Length Human GLDN Protein, C-Flag-tagged

• Cat.No.: GLDN-328HFL
• Product Overview: Recombinant Full Length Human GLDN Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a protein that contains olfactomedin-like and collagen-like domains. The encoded protein, which exists in both transmembrane and secreted forms, promotes formation of the nodes of Ranvier in the peripheral nervous system. Mutations in this gene cause a form of lethal congenital contracture syndrome in human patients. Autoantibodies to the encoded protein have been identified in sera form patients with multifocal motor neuropathy.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 58.8 kDa
• AA Sequence: MARGAEGGRGDAGWGLRGALAAVAL LSALNAAGTVFALCQWRGLSSALRA LEAQRGREQREDSALRSFLA ELSRAPRGASAPPQDPASSARNKRS HSGEPAPHIRAESHDMLMMMTYSMV PIRVMVDLCNSTKGICLTGP SGPPGPPGAGGLPGHNGLDGQPGPQ GPKGEKGANGKRGKMGIPGAAGNPG ERGEKGDHGELGLQGNEGPP GQKGEKGDKGDVSNDVLLAGAKGDQ GPPGPPGPPGPPGPPGPPGSRRAKG PRQPSMFNGQCPGETCAIPN DDTLVGKADEKASEHHSPQAESMIT SIGNPVQVLKVTETFGTWIRESANK SDDRIWVTEHFSGIMVKEFK DQPSLLNGSYTFIHLPYYFHGCGHV VYNNSLYYHKGGSNTLVRFEFGQET SQTLKLENALYFDRKYLFAN SKTYFNLAVDEKGLWIIYASSVDGS SILVAQLDERTFSVVQHVNTTYPKS KAGNAFIARGILYVTDTKDM
  RVTFAFDLLGGKQINANFDLRTSQS VLAMLAYNMRDQHLYSWEDGHLMLY PVQFLSTTLNQTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane

Gene Information

• Gene Name: GLDN gliomedin [ Homo sapiens (human) ]
• Official Symbol: GLDN
• Synonyms: CLOM; COLM; CRGL2; CRG-L2; LCCS11; UNC-112; UNC-122
• Gene ID: 342035
• mRNA Refseq: NM_181789.4
• Protein Refseq: NP_861454.2
• MIM: 608603
• UniProt ID: Q6ZMI3