Recombinant Full Length Human GMPS Protein, GST-tagged

• Cat.No.: GMPS-5422HF
• Product Overview: Human GMPS full-length ORF ( AAH12178, 1 a.a. - 693 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 101.97 kDa
• Protein Length: 693 amino acids
• AA Sequence: MALCNGDSKLENAGGDLKDGHHHYE GAVVILDAGAQYGKVIDRRVRELFV QSEIFPLETPAFAIKEQGFRAIIIS GGPNSVYAEDAPWFDPAIFTIGKPV LGICYGMQMMNKVFGGTVHKKSVRE DGVFNISVDNTCSLFRGLQKEEVVL LTHGDSVDKVADGFKVVARSGNIVA GIANESKKLYGAQFHPEVGLTENGK VILKNFLYDIAGCSGTFTVQNRELE CIREIKERVGTSKVLVLLSGGVDST VCTALLNRALNQEQVIAVHIDNGFM RKRESQSVEEALKKLGIQVKVINAA HSFYNGTTTLPISDEDRTPRKRISK TLNMTTSPEEKRKIIGDTFVKIANE VIGEMNLKPEEVFLAQGTLRPDLIE SASLVASGKAELIKTHHNDTELIRK LREEGKVIEPLKDFHKDEVRILGRE LGLPEELVSRHPFPGPGLAIRVICA EEPYICKDFPETNNILKIVADFSAS VKKPHTLLQRVKACTTEEDQEKLMQ ITSLHSLNAFLLPIKTVGVQGDCRS YSYVCGISSKDEPDWESLIFLARLI PRMCHNVNRVVYIFGPPVKEPPTDV TPTFLTTGVLSTLRQADFEAHNILR ESGYAGKISQMPVILTPLHFDRDPL QKQPSCQRSVVIRTFITSDFMTGIP ATPGNEIPVEVVLKMVTEIKKIPGI SRIMYDLTSKPPGTTEWE
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GMPS guanine monphosphate synthetase [ Homo sapiens ]
• Official Symbol: GMPS
• Synonyms: GMPS; guanine monphosphate synthetase; GMP synthase [glutamine-hydrolyzing]; GMP synthase; GMP synthetase; MLL/GMPS fusion protein; glutamine amidotransferase; guanosine 5-monophosphate synthase
• Gene ID: 8833
• mRNA Refseq: NM_003875
• Protein Refseq: NP_003866
• MIM: 600358
• UniProt ID: P49915