Recombinant Full Length Human GSDMD Protein, His tagged

• Cat.No.: GSDMD-12HFL
• Product Overview: GSDMD Protein, Human (His) is the recombinant human-derived GSDMD protein, expressed by E. coli, with N-6*His tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-484 aa
• Description: Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.
• Form: Lyophilized powder
• Molecular Mass: 57 kDa
• Endotoxin: <1 EU/μg by LAL
• Purity: > 90% by SDS-PAGE
• Storage: Stored at -20 centigrade for 2 years from date of receipt. After reconstitution, it is stable at 4 centigrade for 1 week or -20 centigrade for longer (with carrier protein). It is recommended to freeze aliquots at -20 or -80 centigrade for extended storage.
• Shipping: Room temperature in continental US; may vary elsewhere.
• Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
• Storage Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, 6% trehalose, pH 7.4.

Gene Information

• Gene Name: GSDMD gasdermin D [ Homo sapiens (human) ]
• Official Symbol: GSDMD
• Synonyms: GSDMD; gasdermin D; DF5L; DFNA5L; FKSG10; GSDMDC1; gasdermin-D; gasdermin domain containing 1; gasdermin domain-containing protein 1
• Gene ID: 79792
• mRNA Refseq: NM_024736
• Protein Refseq: NP_079012
• MIM: 617042
• UniProt ID: P57764