Recombinant Full Length Human GYS2 Protein, C-Flag-tagged

• Cat.No.: GYS2-660HFL
• Product Overview: Recombinant Full Length Human GYS2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene, liver glycogen synthase, catalyzes the rate-limiting step in the synthesis of glycogen - the transfer of a glucose molecule from UDP-glucose to a terminal branch of the glycogen molecule. Mutations in this gene cause glycogen storage disease type 0 (GSD-0) - a rare type of early childhood fasting hypoglycemia with decreased liver glycogen content.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 80.8 kDa
• AA Sequence: MLRGRSLSVTSLGGLPQWEVEELPV EELLLFEVAWEVTNKVGGIYTVIQT KAKTTADEWGENYFLIGPYF EHNMKTQVEQCEPVNDAVRRAVDAM NKHGCQVHFGRWLIEGSPYVVLFDI GYSAWNLDRWKGDLWEACSV GIPYHDREANDMLIFGSLTAWFLKE VTDHADGKYVVAQFHEWQAGIGLIL SRARKLPIATIFTTHATLLG RYLCAANIDFYNHLDKFNIDKEAGE RQIYHRYCMERASVHCAHVFTTVSE ITAIEAEHMLKRKPDVVTPN GLNVKKFSAVHEFQNLHAMYKARIQ DFVRGHFYGHLDFDLEKTLFLFIAG RYEFSNKGADIFLESLSRLN FLLRMHKSDITVVVFFIMPAKTNNF NVETLKGQAVRKQLWDVAHSVKEKF GKKLYDALLRGEIPDLNDIL DRDDLTIMKRAIFSTQRQSLPPVTT HNMIDDSTDPILSTIRRIGLFNNRT DRVKVILHPEFLSSTSPLLP MDYEEFVRGCHLGVFPSYYEPWGYT PAECTVMGIPSVTTNLSGFGCFMQE HVADPTAYGIYIVDRRFRSP DDSCNQLTKFLYGFCKQSRRQRIIQ RNRTERLSDLLDWRYLGRYYQHARH LTLSRAFPDKFHVELTSPPT TEGFKYPRPSSVPPSPSGSQASSPQ SSDVEDEVEDERYDEEEEAERDRLN IKSPFSLSHVPHGKKKLHGE
  YKNTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Insulin signaling pathway, Starch and sucrose metabolism

Gene Information

• Gene Name: GYS2 glycogen synthase 2 [ Homo sapiens (human) ]
• Official Symbol: GYS2
• Synonyms: glycogen synthase 2 (liver)
• Gene ID: 2998
• mRNA Refseq: NM_021957.4
• Protein Refseq: NP_068776.2
• MIM: 138571
• UniProt ID: P54840