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Recombinant Full Length Human GZMA Protein, C-Flag-tagged

Cat.No. : GZMA-1713HFL
Product Overview : Recombinant Full Length Human GZMA Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.
  • Specification
  • Gene Information
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Description : Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.
Source : Mammalian cells
Species : Human
Tag : Flag
Form : 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 28.8 kDa
AA Sequence : MRNSYRFLASSLSVVVSLLLIPEDV CEKIIGGNEVTPHSRPYMVLLSLDR KTICAGALIAKDWVLTAAHC NLNKRSQVILGAHSITREEPTKQIM LVKKEFPYPCYDPATREGDLKLLQL TEKAKINKYVTILHLPKKGD DVKPGTMCQVAGWGRTHNSASWSDT LREVNITIIDRKVCNDRNHYNFNPV IGMNMVCAGSLRGGRDSCNG
DSGSPLLCEGVFRGVTSFGLENKCG DPRGPGVYILLSKKHLNWIIMTIKG AVTRTRPLEQKLISEEDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining.
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 ug/mL as determined by microplate BCA method.
Preparation : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families : Druggable Genome, Protease, Secreted Protein
Protein Pathways : Neuroactive ligand-receptor interaction
Gene Name : GZMA granzyme A [ Homo sapiens (human) ]
Official Symbol : GZMA
Synonyms : HFSP; CTLA3
Gene ID : 3001
mRNA Refseq : NM_006144.4
Protein Refseq : NP_006135.2
MIM : 140050
UniProt ID : P12544

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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