Recombinant Full Length Human HINT1 Protein, C-Flag-tagged

• Cat.No.: HINT1-1206HFL
• Product Overview: Recombinant Full Length Human HINT1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a protein that hydrolyzes purine nucleotide phosphoramidates substrates, including AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif. This gene is considered a tumor suppressor gene. In addition, mutations in this gene can cause autosomal recessive neuromyotonia and axonal neuropathy. There are several related pseudogenes on chromosome 7. Several transcript variants have been observed.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 13.6 kDa
• AA Sequence: MADEIAKAQVARPGGDTIFGKIIRK EIPAKIIFEDDRCLAFHDISPQAPT HFLVIPKKHISQISVAEDDDESLLG HLMIVGKKCAADLGLNKGYRMVVNE GSDGGQSVYHVHLHVLGGRQMHWPP G TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: HINT1 histidine triad nucleotide binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: HINT1
• Synonyms: HINT; NMAN; PKCI-1; PRKCNH1
• Gene ID: 3094
• mRNA Refseq: NM_005340.7
• Protein Refseq: NP_005331.1
• MIM: 601314
• UniProt ID: P49773