Recombinant Full Length Human HNF4A Protein, C-Flag-tagged
Cat.No. : | HNF4A-88HFL |
Product Overview : | Recombinant Full Length Human HNF4A Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 52.6 kDa |
AA Sequence : | MRLSKTLVDMDMADYSAALDPAYTT LEFENVQVLTMGNDTSPSEGTNLNA PNSLGVSALCAICGDRATGK HYGASSCDGCKGFFRRSVRKNHMYS CRFSRQCVVDKDKRNQCRYCRLKKC FRAGMKKEAVQNERDRISTR RSSYEDSSLPSINALLQAEVLSRQI TSPVSGINGDIRAKKIASIADVCES MKEQLLVLVEWAKYIPAFCE LPLDDQVALLRAHAGEHLLLGATKR SMVFKDVLLLGNDYIVPRHCPELAE MSRVSIRILDELVLPFQELQ IDDNEYAYLKAIIFFDPDAKGLSDP GKIKRLRSQVQVSLEDYINDRQYDS RGRFGELLLLLPTLQSITWQ MIEQIQFIKLFGMAKIDNLLQEMLL GGSPSDAPHAHHPLHPHLMQEHMGT NVIVANTMPTHLSNGQMCEW PRPRGQAATPETPQPSPPGGSGSEP YKLLPGAVATIVKPLSAIPQPTITK QEVITRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, ES Cell Differentiation/IPS, Nuclear Hormone Receptor, Transcription Factors |
Protein Pathways : | Maturity onset diabetes of the young |
Gene Name : | HNF4A hepatocyte nuclear factor 4 alpha [ Homo sapiens (human) ] |
Official Symbol : | HNF4A |
Synonyms : | TCF; HNF4; MODY; FRTS4; MODY1; NR2A1; TCF14; HNF4a7; HNF4a8; HNF4a9; NR2A21; TCF-14; HNF4alpha |
Gene ID : | 3172 |
mRNA Refseq : | NM_000457.6 |
Protein Refseq : | NP_000448.3 |
MIM : | 600281 |
UniProt ID : | P41235 |
Products Types
◆ Recombinant Protein | ||
HNF4A-4255M | Recombinant Mouse HNF4A Protein, His (Fc)-Avi-tagged | +Inquiry |
HNF4A-1084H | Recombinant Human HNF4A Protein, His (Fc)-Avi-tagged | +Inquiry |
Hnf4a-1147M | Recombinant Mouse Hnf4a Protein, MYC/DDK-tagged | +Inquiry |
HNF4A-4895H | Recombinant Human HNF4A Protein, GST-tagged | +Inquiry |
HNF4A-28507TH | Recombinant Human HNF4A | +Inquiry |
◆ Lysates | ||
HNF4A-5456HCL | Recombinant Human HNF4A 293 Cell Lysate | +Inquiry |
HNF4A-5458HCL | Recombinant Human HNF4A 293 Cell Lysate | +Inquiry |
HNF4A-5459HCL | Recombinant Human HNF4A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket