Recombinant Full Length Human IDUA Protein, C-Flag-tagged
Cat.No. : | IDUA-458HFL |
Product Overview : | Recombinant Full Length Human IDUA Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Bio-activity : | Not mentioned |
Molecular Mass : | 70 kDa |
AA Sequence : | MRPLRPRAALLALLASLLAAPPVAP AEAPHLVHVDAARALWPLRRFWRST GFCPPLPHSQADQYVLSWDQ QLNLAYVGAVPHRGIKQVRTHWLLE LVTTRGSTGRGLSYNFTHLDGYLDL LRENQLLPGFELMGSASGHF TDFEDKQQVFEWKDLVSSLARRYIG RYGLAHVSKWNFETWNEPDHHDFDN VSMTMQGFLNYYDACSEGLR AASPALRLGGPGDSFHTPPRSPLSW GLLRHCHDGTNFFTGEAGVRLDYIS LHRKGARSSISILEQEKVVA QQIRQLFPKFADTPIYNDEADPLVG WSLPQPWRADVTYAAMVVKVIAQHQ NLLLANTTSAFPYALLSNDN AFLSYHPHPFAQRTLTARFQVNNTR PPHVQLLRKPVLTAMGLLALLDEEQ LWAEVSQAGTVLDSNHTVGV LASAHRPQGPADAWRAAVLIYASDD TRAHPNRSVAVTLRLRGVPPGPGLV YVTRYLDNGLCSPDGEWRRL GRPVFPTAEQFRRMRAAEDPVAAAP RPLPAGGRLTLRPALRLPSLLLVHV CARPEKPPGQVTRLRALPLT QGQLVLVWSDEHVGSKCLWTYEIQF SQDGKAYTPVSRKPSTFNLFVFSPD TGAVSGSYRVRALDYWARPG PFSDPVPYLEVPVPRGPPSPGNPSG PTRTRRLEQKLISEEDLAANDILDY KDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Glycosaminoglycan degradation, Lysosome, Metabolic pathways |
Gene Name : | IDUA alpha-L-iduronidase [ Homo sapiens (human) ] |
Official Symbol : | IDUA |
Synonyms : | IDA; MPS1; MPSI |
Gene ID : | 3425 |
mRNA Refseq : | NM_000203.5 |
Protein Refseq : | NP_000194.2 |
MIM : | 252800 |
UniProt ID : | P35475 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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