Recombinant Full Length Human IGF2BP2 Protein, C-Flag-tagged

• Cat.No.: IGF2BP2-92HFL
• Product Overview: Recombinant Full Length Human IGF2BP2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 65.9 kDa
• AA Sequence: MNKLYIGNLSPAVTADDLRQLFGDR KLPLAGQVLLKSGYAFVDYPDQNWA IRAIETLSGKVELHGKIMEV DYSVSKKLRSRKIQIRNIPPHLQWE VLDGLLAQYGTVENVEQVNTDTETA VVNVTYATREEAKIAMEKLS GHQFENYSFKISYIPDEEVSSPSPP QRAQRGDHSSREQGHAPGGTSQARQ IDFPLRILVPTQFVGAIIGK EGLTIKNITKQTQSRVDIHRKENSG AAEKPVTIHATPEGTSEACRMILEI MQKEADETKLAEEIPLKILA HNGLVGRLIGKEGRNLKKIEHETGT KITISSLQDLSIYNPERTITVKGTV EACASAEIEIMKKLREAFEN DMLAVNQQANLIPGLNLSALGIFST GLSVLSPPAGPRGAPPAAPYHPFTT HSGYFSSLYPHHQFGPFPHH HSYPEQEIVNLFIPTQAVGAIIGKK GAHIKQLARFAGASIKIAPAEGPDV SERMVIITGPPEAQFKAQGR IFGKLKEENFFNPKEEVKLEAHIRV PSSTAGRVIGKGGKTVNELQNLTSA EVIVPRDQTPDENEEVIVRI
  IGHFFASQTAQRKIREIVQQVKQQE QKYPQGVASQRSKTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: IGF2BP2 insulin like growth factor 2 mRNA binding protein 2 [ Homo sapiens (human) ]
• Official Symbol: IGF2BP2
• Synonyms: IMP2; IMP-2; VICKZ2
• Gene ID: 10644
• mRNA Refseq: NM_006548.6
• Protein Refseq: NP_006539.3
• MIM: 608289
• UniProt ID: Q9Y6M1