Recombinant Full Length Human IGFALS Protein, C-Flag-tagged

• Cat.No.: IGFALS-703HFL
• Product Overview: Recombinant Full Length Human IGFALS Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 63.2 kDa
• AA Sequence: MALRKGGLALALLLLSWVALGPRSL EGADPGTPGEAEGPACPAACVCSYD DDADELSVFCSSRNLTRLPD GVPGGTQALWLDGNNLSSVPPAAFQ NLSSLGFLNLQGGQLGSLEPQALLG LENLCHLHLERNQLRSLALG TFAHTPALASLGLSNNRLSRLEDGL FEGLGSLWDLNLGWNSLAVLPDAAF RGLGSLRELVLAGNRLAYLQ PALFSGLAELRELDLSRNALRAIKA NVFVQLPRLQKLYLDRNLIAAVAPG AFLGLKALRWLDLSHNRVAG LLEDTFPGLLGLRVLRLSHNAIASL RPRTFKDLHFLEELQLGHNRIRQLA ERSFEGLGQLEVLTLDHNQL QEVKAGAFLGLTNMAVMNLSGNCLR NLPEQVFRGLGKLHSLHLEGSCLGR IRPHTFTGLSGLRRLFLKDN GLVGIEEQSLWGLAELLELDLTSNQ LTHLPHRLFQGLGKLEYLLLSRNRL AELPADALGPLQRAFWLDVS HNRLEALPNSLLAPLGRLRYLSLRN NSLRTFTPQPPGLERLWLEGNPWDC GCPLKALRDFALQNPSAVPR
  FVQAICEGDDCQPPAYTYNNITCAS PPEVVGLDLRDLSEAHFAPCTRTRP LEQKLISEEDLAANDILDYKDDDDK V
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein

Gene Information

• Gene Name: IGFALS insulin like growth factor binding protein acid labile subunit [ Homo sapiens (human) ]
• Official Symbol: IGFALS
• Synonyms: ALS; ACLSD
• Gene ID: 3483
• mRNA Refseq: NM_004970.3
• Protein Refseq: NP_004961.1
• MIM: 601489
• UniProt ID: P35858