Recombinant Full Length Human IL27RA Protein, C-Flag-tagged

• Cat.No.: IL27RA-876HFL
• Product Overview: Recombinant Full Length Human IL27RA Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 69.3 kDa
• AA Sequence: MRGGRGAPFWLWPLPKLALLPLLWV LFQRTRPQGSAGPLQCYGVGPLGDL NCSWEPLGDLGAPSELHLQ SQKYRSNKTQTVAVAAGRSWVAIPR EQLTMSDKLLVWGTKAGQPLWPPVF VNLETQMKPNAPRLGPDVD FSEDDPLEATVHWAPPTWPSHKVLI CQFHYRRCQEAAWTLLEPELKTIPL TPVEIQDLELATGYKVYGR CRMEKEEDLWGEWSPILSFQTPPSA PKDVWVSGNLCGTPGGEEPLLLWKA PGPCVQVSYKVWFWVGGRE LSPEGITCCCSLIPSGAEWARVSAV NATSWEPLTNLSLVCLDSASAPRSV AVSSIAGSTELLVTWQPGP GEPLEHVVDWARDGDPLEKLNWVRL PPGNLSALLPGNFTVGVPYRITVTA VSASGLASASSVWGFREEL APLVGPTLWRLQDAPPGTPAIAWGE VPRHQLRGHLTHYTLCAQSGTSPSV CMNVSGNTQSVTLPDLPWG PCELWVTASTIAGQGPPGPILRLHL PDNTLRWKVLPGILFLWGLFLLGCG LSLATSGRCYHLRHKVLPR WVWEKVPDPANSSSGQPHMEQVPEA QPLGDLPILEVEEMEPPPVMESSQP AQATAPLDSGYEKHFLPTP
  EELGLLGPPRPQVLASGPTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane

Gene Information

• Gene Name: IL27RA interleukin 27 receptor subunit alpha [ Homo sapiens (human) ]
• Official Symbol: IL27RA
• Synonyms: CRL1; TCCR; WSX1; IL27R; IL-27RA; zcytor1
• Gene ID: 9466
• mRNA Refseq: NM_004843.4
• Protein Refseq: NP_004834.1
• MIM: 605350
• UniProt ID: Q6UWB1