| Cat.No. : |
IL27RA-876HFL
Optional Service: Optional requirements on this protein
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| Product Overview : |
Recombinant Full Length Human IL27RA Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
| Description : |
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. |
| Source : |
Mammalian cells |
| Species : |
Human |
| Tag : |
Flag |
| Form : |
25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Molecular Mass : |
69.3 kDa |
| AA Sequence : |
MRGGRGAPFW LWPLPKLALL PLLWVLFQRT RPQGSAGPLQ CYGVGPLGDL NCSWEPLGDL GAPSELHLQ SQKYRSNKTQ TVAVAAGRSW VAIPREQLTM SDKLLVWGTK AGQPLWPPVF VNLETQMKPN APRLGPDVD FSEDDPLEAT VHWAPPTWPS HKVLICQFHY RRCQEAAWTL LEPELKTIPL TPVEIQDLEL ATGYKVYGR CRMEKEEDLW GEWSPILSFQ TPPSAPKDVW VSGNLCGTPG GEEPLLLWKA PGPCVQVSYK VWFWVGGRE LSPEGITCCC SLIPSGAEWA RVSAVNATSW EPLTNLSLVC LDSASAPRSV AVSSIAGSTE LLVTWQPGP GEPLEHVVDW ARDGDPLEKL NWVRLPPGNL SALLPGNFTV GVPYRITVTA VSASGLASAS SVWGFREEL APLVGPTLWR LQDAPPGTPA IAWGEVPRHQ LRGHLTHYTL CAQSGTSPSV CMNVSGNTQS VTLPDLPWG PCELWVTAST IAGQGPPGPI LRLHLPDNTL RWKVLPGILF LWGLFLLGCG LSLATSGRCY HLRHKVLPR WVWEKVPDPA NSSSGQPHME QVPEAQPLGD LPILEVEEME PPPVMESSQP AQATAPLDSG YEKHFLPTPE ELGLLGPPRP QVLASGPTRT RPLEQKLISE EDLAANDILD YKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining. |
| Stability : |
Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : |
Store at -80 centigrade. |
| Concentration : |
>50 ug/mL as determined by microplate BCA method. |
| Preparation : |
Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Protein Families : |
Druggable Genome, Transmembrane |
| Figure : |
Coomassie blue staining of purified IL27RA protein.
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.