Recombinant Full Length Human INPP5A Protein, GST-tagged
Cat.No. : | INPP5A-5953HF |
Product Overview : | Human INPP5A full-length ORF ( NP_005530.3, 1 a.a. - 412 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 74.2 kDa |
Protein Length : | 412 amino acids |
AA Sequence : | MAGKAAAPGTAVLLVTANVGSLFDD PENLQKNWLREFYQVVHTHKPHFMA LHCQEFGGKNYEASMSHVDKFVKEL LSSDAMKEYNRARVYLDENYKSQEH FTALGSFYFLHESLKNIYQFDFKAK KYRKVAGKEIYSDTLESTPMLEKEK FPQDYFPECKWSRKGFIRTRWCIAD CAFDLVNIHLFHDASNLVAWETSPS VYSGIRHKALGYVLDRIIDQRFEKV SYFVFGDFNFRLDSKSVVETLCTKA TMQTVRAADTNEVVKLIFRESDNDR KVMLQLEKKLFDYFNQEVFRDNNGT ALLEFDKELSVFKDRLYELDISFPP SYPYSEDARQGEQYMNTRCPAWCDR ILMSPSAKELVLRSESEEKVVTYDH IGPNVCMGDHKPVFLAFRIMPGAGK PHAHVHKCCVVQ |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | INPP5A inositol polyphosphate-5-phosphatase, 40kDa [ Homo sapiens ] |
Official Symbol : | INPP5A |
Synonyms : | INPP5A; inositol polyphosphate-5-phosphatase, 40kDa; inositol polyphosphate 5 phosphatase, 40kD; type I inositol 1,4,5-trisphosphate 5-phosphatase; 5PTASE; 43 kDa inositol polyphosphate 5 phophatase; CTCL tumor antigen HD CL 02; inositol polyphosphate 5 phophatase; 40kDa; InsP3 5 phosphatase; type I inositol 1; 4; 5 trisphosphate 5 phosphatase; InsP3 5-phosphatase; CTCL tumor antigen HD-CL-02; 43 kDa inositol polyphosphate 5-phophatase; inositol trisphosphate-5-phosphatase, 40kD; type I inositol-1,4,5-trisphosphate 5-phophatase; type I inositol-1,4,5-trisphosphate 5-phosphatase; MGC116947; MGC116949; DKFZp434A1721; |
Gene ID : | 3632 |
mRNA Refseq : | NM_005539 |
Protein Refseq : | NP_005530 |
MIM : | 600106 |
UniProt ID : | Q14642 |
Products Types
◆ Recombinant Protein | ||
Inpp5a-3546M | Recombinant Mouse Inpp5a Protein, Myc/DDK-tagged | +Inquiry |
INPP5A-5108H | Recombinant Human INPP5A Protein, GST-tagged | +Inquiry |
INPP5A-1012H | Recombinant Human INPP5A Protein (1-409 aa), His-SUMO-tagged | +Inquiry |
INPP5A-27622TH | Recombinant Human INPP5A | +Inquiry |
INPP5A-012H | Recombinant Human INPP5A Protien, His-tagged | +Inquiry |
◆ Lysates | ||
INPP5A-5199HCL | Recombinant Human INPP5A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionAccording to Entrez, the protein encoded by INPP5A is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase.
INPP5A plays a crucial role in the survival of cerebellar Purkinje cells.
INPP5A specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate.
INPP5A is a phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate.
INPP5A has a specific catalytic domain that is responsible for its phosphatase activity. The structural details of INPP5A are important for understanding its function in inositol phosphate metabolism.
INPP5A functions as a hydrolase.
INPP5A regulates cellular signaling by controlling the levels of inositol phosphates, which are important secondary messengers in many cellular pathways.
Customer Reviews (3)
Write a reviewThe product's rapid action in triggering cellular responses significantly expedited our experiments.
The user-friendly design of the product made it accessible to researchers with varying levels of expertise.
The availability of technical experts for consultations greatly aided in optimizing our experiments.
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