Recombinant Full Length Human INSIG2 Protein, C-Flag-tagged

• Cat.No.: INSIG2-1720HFL
• Product Overview: Recombinant Full Length Human INSIG2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 24.6 kDa
• AA Sequence: MAEGETESPGPKKCGPYISSVTSQS VNLMIRGVVLFFIGVFLALVLNLLQ IQRNVTLFPPDVIASIFSSA WWVPPCCGTASAVIGLLYPCIDRHL GEPHKFKREWSSVMRCVAVFVGINH ASAKVDFDNNIQLSLTLAAL SIGLWWTFDRSRSGFGLGVGIAFLA TVVTQLLVYNGVYQYTSPDFLYVRS WLPCIFFAGGITMGNIGRQL
  AMYECKVIAEKSHQETRTRPLEQKL ISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane

Gene Information

• Gene Name: INSIG2 insulin induced gene 2 [ Homo sapiens (human) ]
• Official Symbol: INSIG2
• Synonyms: INSIG-2
• Gene ID: 51141
• mRNA Refseq: NM_016133.4
• Protein Refseq: NP_057217.2
• MIM: 608660
• UniProt ID: Q9Y5U4