Recombinant Full Length Human ISG15 Protein, C-Flag-tagged

• Cat.No.: ISG15-931HFL
• Product Overview: Recombinant Full Length Human ISG15 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 17.7 kDa
• AA Sequence: MGWDLTVKMLAGNEFQVSLSSSMSV SELKAQITQKIGVHAFQQRLAVHPS GVALQDRVPLASQGLGPGST VLLVVDKCDEPLNILVRNNKGRSST YEVRLTQTVAHLKQQVSGLEGVQDD LFWLTFEGKPLEDQLPLGEY
  GLKPLSTVFMNLRLRGGGTEPGGRS TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: RIG-I-like receptor signaling pathway

Gene Information

• Gene Name: ISG15 ISG15 ubiquitin like modifier [ Homo sapiens (human) ]
• Official Symbol: ISG15
• Synonyms: G1P2; IP17; UCRP; IFI15; IMD38; hUCRP
• Gene ID: 9636
• mRNA Refseq: NM_005101.4
• Protein Refseq: NP_005092.1
• MIM: 147571
• UniProt ID: P05161