Recombinant Full Length Human ITPKA Protein, C-Flag-tagged
Cat.No. : | ITPKA-1222HFL |
Product Overview : | Recombinant Full Length Human ITPKA Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 50.8 kDa |
AA Sequence : | MTLPGGPTGMARPGGARPCSPGLER APRRSVGELRLLFEARCAAVAAAAA AGEPRARGAKRRGGQVPNGL QRAPPAPVIPQLTVTAEEPDVPPTS PGPPERERDCLPAAGSSHLQQPRRL STSSVSSTGSSSLLEDSEDD LLSDSESRSRGNVQLEAGEDVGQKN HWQKIRTMVNLPVISPFKKRYAWVQ LAGHTGSFKAAGTSGLILKR CSEPERYCLARLMADALRGCVPAFH GVVERDGESYLQLQDLLDGFDGPCV LDCKMGVRTYLEEELTKARE RPKLRKDMYKKMLAVDPEAPTEEEH AQRAVTKPRYMQWREGISSSTTLGF RIEGIKKADGSCSTDFKTTR SREQVLRVFEEFVQGDEEVLRRYLN RLQQIRDTLEVSEFFRRHEVIGSSL LFVHDHCHRAGVWLIDFGKT TPLPDGQILDHRRPWEEGNREDGYL LGLDNLIGILASLAERTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Calcium signaling pathway, Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system |
Gene Name : | ITPKA inositol-trisphosphate 3-kinase A [ Homo sapiens (human) ] |
Official Symbol : | ITPKA |
Synonyms : | IP3KA; IP3-3KA |
Gene ID : | 3706 |
mRNA Refseq : | NM_002220.3 |
Protein Refseq : | NP_002211.1 |
MIM : | 147521 |
UniProt ID : | P23677 |
Products Types
◆ Recombinant Protein | ||
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ITPKA-4653M | Recombinant Mouse ITPKA Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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