Recombinant Full Length Human KDM1B Protein, GST-tagged

• Cat.No.: KDM1B-1427HF
• Product Overview: Human AOF1 full-length ORF (BAC03663.1, 1 a.a. - 619 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (Karytinos et al., 2009 [PubMed 19407342]).[supplied by OMIM, Oct 2009]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 95 kDa
• Protein Length: 619 amino acids
• AA Sequence: MLILPPLLKD SVAAPLLSAY YPDCVGMSPS CTSTNRAAAT GNASPGKLEH SKAALSVHVP GMNRYFQPFY QPNECGKALC VRPDVMELDE LYEFPEYSRD PTMYLALRNL ILALWYTNCK EALTPQKCIP HIIVRGLVRI RCVQEVERIL YFMTRKGLIN TGVLSVGADQ YLLPKDYHNK SVIIIGAGPA GLAAARQLHN FGIKVTVLEA KDRIGGRVWD DKSFKGVTVG RGAQIVNGCI NNPVALMCEQ LGISMHKFGE RCDLIQEGGR ITDPTIDKRM DFHFNALLDV VSEWRKDKTQ LQDVPLGEKI EEIYKAFIKE SGIQFSELEG QVLQFHLSNL EYACGSNLHQ VSARSWDHNE FFAQFAGDHT LLTPGYSVII EKLAEGLDIQ LKSPVQCIDY SGDEVQVTTT DGTGYSAQKV LVTVPLALLQ KGAIQFNPPL SEKKMKAINS LGAGIIEKIA LQFPYRFWDS KVQGADFFGH VPPSASKRGL FAVFYDMDPQ KKHSVLMSVI AGEAVASVRT LDDKQVLQQC MATLRELFKE QEVPDPTKYF VTRWSTDPWI QMAYSFVKTG GSGEAYDIIA EDIQGTVFFA GEATNRHFPQ TVTGAYLSGV REASKIAAF
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: KDM1B lysine (K)-specific demethylase 1B [ Homo sapiens ]
• Official Symbol: KDM1B
• Synonyms: KDM1B; lysine (K)-specific demethylase 1B; amine oxidase (flavin containing) domain 1 , amine oxidase, flavin containing 1 , AOF1, C6orf193, chromosome 6 open reading frame 193; lysine-specific histone demethylase 1B; bA204B7.3; dJ298J15.2; FLJ33898; FLJ34109; FLJ43328; LSD2; amine oxidase, flavin containing 1; lysine-specific histone demethylase 2; amine oxidase (flavin containing) domain 1; flavin-containing amine oxidase domain-containing protein 1; AOF1; C6orf193; DKFZp686I0412
• Gene ID: 221656
• mRNA Refseq: NM_153042
• Protein Refseq: NP_694587
• MIM: 613081
• UniProt ID: Q8NB78