Recombinant Full Length Human LEFTY1 Protein, His tagged

• Cat.No.: LEFTY1-01H
• Product Overview: Purified recombinant protein of Human left-right determination factor 1 (LEFTY1), full length, with N-terminal HIS tag, expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-366 aa
• Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene.
• Form: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Molecular Mass: 38.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80 centigrade. Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Concentration: > 0.05 μg/μL as determined by microplate BCA method

Gene Information

• Gene Name: LEFTY1 left-right determination factor 1 [ Homo sapiens (human) ]
• Official Symbol: LEFTY1
• Synonyms: LEFTY1; left-right determination factor 1; left right determination, factor B, LEFTB; LEFTYB; protein lefty-1; protein lefty-B; left-right determination factor B; left-right determination, factor B; LEFTB
• Gene ID: 10637
• mRNA Refseq: NM_020997
• Protein Refseq: NP_066277
• MIM: 603037
• UniProt ID: O75610