Recombinant Full Length Human LRPPRC Protein, C-Flag-tagged

• Cat.No.: LRPPRC-1879HFL
• Product Overview: Recombinant Full Length Human LRPPRC Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 157.7 kDa
• AA Sequence: MAALLRSARWLLRAGAAPRLPLSLR LLPGGPGRLHAASYLPAARAGPVAG GLLSPARLYAIAAKEKDIQE ESTFSSRKISNQFDWALMRLDLSVR RTGRIPKKLLQKVFNDTCRSGGLGG SHALLLLRSCGSLLPELKLE ERTEFAHRIWDTLQKLGAVYDVSHY NALLKVYLQNEYKFSPTDFLAKMEE ANIQPNRVTYQRLIASYCNV GDIEGASKILGFMKTKDLPVTEAVF SALVTGHARAGDMENAENILTVMRD AGIEPGPDTYLALLNAYAEK GDIDHVKQTLEKVEKSELHLMDRDL LQIIFSFSKAGYPQYVSEILEKVTC ERRYIPDAMNLILLLVTEKL EDVALQILLACPVSKEDGPSVFGSF FLQHCVTMNTPVEKLTDYCKKLKEV QMHSFPLQFTLHCALLANKT DLAKALMKAVKEEGFPIRPHYFWPL LVGRRKEKNVQGIIEILKGMQELGV HPDQETYTDYVIPCFDSVNS ARAILQENGCLSDSDMFSQAGLRSE AANGNLDFVLSFLKSNTLPISLQSI RSSLLLGFRRSMNINLWSEI TELLYKDGRYCQEPRGPTEAVGYFL YNLIDSMSDSEVQAKEEHLRQYFHQ LEKMNVKIPENIYRGIRNLL ESYHVPELIKDAHLLVESKNLDFQK TVQLTSSELESTLETLKAENQPIRD VLKQLILVLCSEENMQKALE LKAKYESDMVTGGYAALINLCCRHD KVEDALNLKEEFDRLDSSAVLDTGK YVGLVRVLAKHGKLQDAINI LKEMKEKDVLIKDTTALSFFHMLNG AALRGEIETVKQLHEAIVTLGLAEP STNISFPLVTVHLEKGDLST ALEVAIDCYEKYKVLPRIHDVLCKL VEKGETDLIQKAMDFVSQEQGEMVM LYDLFFAFLQTGNYKEAKKI IETPGIRARSARLQWFCDRCVANNQ VETLEKLVELTQKLFECDRDQMYYN LLKLYKINGDWQRADAVWNK IQEENVIPREKTLRLLAEILREGNQ EVPFDVPELWYEDEKHSLNSSSAST TEPDFQKDILIACRLNQKKG AYDIFLNAKEQNIVFNAETYSNLIK LLMSEDYFTQAMEVKAFAETHIKGF TLNDAANSRLIITQVRRDYL KEAVTTLKTVLDQQQTPSRLAVTRV IQALAMKGDVENIEVVQKMLNGLED SIGLSKMVFINNIALAQIKN NNIDAAIENIENMLTSENKVIEPQY FGLAYLFRKVIEEQLEPAVEKISIM AERLANQFAIYKPVTDFFLQ LVDAGKVDDARALLQRCGAIAEQTP ILLLFLLRNSRKQGKASTVKSVLEL IPELNEKEEAYNSLMKSYVS EKDVTSAKALYEHLTAKNTKLDDLF LKRYASLLKYAGEPVPFIEPPESFE FYAQQLRKLRENSS TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: LRPPRC leucine rich pentatricopeptide repeat containing [ Homo sapiens (human) ]
• Official Symbol: LRPPRC
• Synonyms: LSFC; GP130; LRP130; MC4DN5; CLONE-23970
• Gene ID: 10128
• mRNA Refseq: NM_133259.4
• Protein Refseq: NP_573566.2
• MIM: 607544
• UniProt ID: P42704