Recombinant Full Length Human MACC1 Protein, C-Flag-tagged

• Cat.No.: MACC1-823HFL
• Product Overview: Recombinant Full Length Human MACC1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 96.5 kDa
• AA Sequence: MLITERKHFRSGRIAQSMSEANLID MEAGKLSKSCNITECQDPDLLHNWP DAFTLRGNNASKVANPFWNQ LSASNPFLDDITQLRNNRKRNNISI LKEDPFLFCREIENGNSFDSSGDEL DVHQLLRQTSSRNSGRSKSV SELLDILDDTAHAHQSIHNSDQILL HDLEWLKNDREAYKMAWLSQRQLAR SCLDLNTISQSPGWAQTQLA EVTIACKVNHQGGSVQLPESDITVH VPQGHVAVGEFQEVSLRAFLDPPHM LNHDLSCTVSPLLEIMLGNL NTMEALLLEMKIGAEVRKDPFSQVM TEMVCLHSLGKEGPFKVLSNCYIYK DTIQVKLIDLSQVMYLVVAA QAKALPSPAATIWDYIHKTTSIGIY GPKYIHPSFTVVLTVCGHNYMPGQL TISDIKKGGKNISPVVFQLW GKQSFLLDKPQDLSISIFSCDPDFE VKTEGERKEIKQKQLEAGEVVHQQF LFSLVEHREMHLFDFCVQVE PPNGEPVAQFSITTPDPTPNLKRLS NLPGYLQKKEEIKSAPLSPKILVKY PTFQDKTLNFSNYGVTLKAV LRQSKIDYFLEYFKGDTIALLGEGK VKAIGQSKVKEWYVGVLRGKIGLVH CKNVKVISKEQVMFMSDSVF TTRNLLEQIVLPLKKLTYIYSVVLT LVSEKVYDWKVLADVLGYSHLSLED FDQIQADKESEKVSYVIKKL KEDCHTERNTRKFLYELIVALLKMD CQELVARLIQEAAVLTSAVKLGKGW RELAEKLVRLTKQQMEAYEI PHRGNTGDVAVEMMWKPAYDFLYTW SAHYGNNYRDVLQDLQSALDRMKNP VTKHWRELTGVLILVNSLEV
  LRVTAFSTSEEVTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: MACC1 MET transcriptional regulator MACC1 [ Homo sapiens (human) ]
• Official Symbol: MACC1
• Synonyms: 7A5; SH3BP4L
• Gene ID: 346389
• mRNA Refseq: NM_182762.4
• Protein Refseq: NP_877439.3
• MIM: 612646
• UniProt ID: Q6ZN28