Recombinant Full Length Human MAT1A Protein, C-Flag-tagged

• Cat.No.: MAT1A-1067HFL
• Product Overview: Recombinant Full Length Human MAT1A Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 43.5 kDa
• AA Sequence: MNGPVDGLCDHSLSEGVFMFTSESV GEGHPDKICDQISDAVLDAHLKQDP NAKVACETVCKTGMVLLCGE ITSMAMVDYQRVVRDTIKHIGYDDS AKGFDFKTCNVLVALEQQSPDIAQC VHLDRNEEDVGAGDQGLMFG YATDETEECMPLTIILAHKLNARMA DLRRSGLLPWLRPDSKTQVTVQYMQ DNGAVIPVRIHTIVISVQHN EDITLEEMRRALKEQVIRAVVPAKY LDEDTVYHLQPSGRFVIGGPQGDAG VTGRKIIVDTYGGWGAHGGG AFSGKDYTKVDRSAAYAARWVAKSL VKAGLCRRVLVQVSYAIGVAEPLSI SIFTYGTSQKTERELLDVVH
  KNFDLRPGVIVRDLDLKKPIYQKTA CYGHFGRSEFPWEVPRKLVFTRTRP LEQKLISEEDLAANDILDYKDDDDK V
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Cysteine and methionine metabolism, Metabolic pathways, Selenoamino acid metabolism

Gene Information

• Gene Name: MAT1A methionine adenosyltransferase 1A [ Homo sapiens (human) ]
• Official Symbol: MAT1A
• Synonyms: MAT; SAMS; MATA1; SAMS1
• Gene ID: 4143
• mRNA Refseq: NM_000429.3
• Protein Refseq: NP_000420.1
• MIM: 610550
• UniProt ID: Q00266