Recombinant Full Length Human MICAL1 Protein, C-Myc/DDK-tagged

• Cat.No.: MICAL1-873HFL
• Product Overview: Recombinant Full Length protein of human microtubule associated monoxygenase, calponin and LIM domain containing 1 (MICAL1) with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Description: This gene encodes an enzyme that oxidizes methionine residues on actin, thereby promoting depolymerization of actin filaments. This protein interacts with and regulates signalling by NEDD9/CAS-L (neural precursor cell expressed, developmentally down-regulated 9). Alternative splicing results in multiple transcript variants.
• Source: HEK293T
• Species: Human
• Tag: C-Myc/DDK
• Molecular Mass: 117.7 kDa
• AA Sequence: MASPTSTNPAHAHFESFLQAQLCQD VLSSFQELCGALGLEPGGGLPQYHK IKDQLNYWSAKSLWTKLDKRAGQPV YQQGRACTSTKCLVVGAGPCGLRVA VELALLGARVVLVEKRTKFSRHNVL HLWPFTIHDLRALGAKKFYGRFCTG TLDHISIRQLQLLLLKVALLLGVEI HWGVTFTGLQPPPRKGSGWRAQLQP NPPAQLANYEFDVLISAAGGKFVPE GFKVREMRGKLAIGITANFVNGRTV EETQVPEISGVARIYNQSFFQSLLK ATGIDLENIVYYKDDTHYFVMTAKK QCLLRLGVLRQDWPDTNRLLGSANV VPEALQRFTRAAADFATHGKLGKLE FAQDAHGQPDVSAFDFTSMMRAESS ARVQEKHGARLLLGLVGDCLVEPFW PLGTGVARGFLAAFDAAWMVKRWAE GAESLEVLAERESLYQLLSQTSPEN MHRNVAQYGLDPATRYPNLNLRAVT PNQVRDLYDVLAKEPVQRNNDKTDT GMPATGSAGTQEELLRWCQEQTAGY PGVHVSDLSSSWADGLALCALVYRL QPGLLEPSELQGLGALEATAWALKV AENELGITPVVSAQAVVAGSDPLGL IAYLSHFHSAFKSMAHSPGPVSQAS PGTSSAVLFLSKLQRTLQRSRAKEN AEDAGGKKLRLEMEAETPSTEVPPD PEPGVPLTPPSQHQEAGAGDLCALC GEHLYVLERLCVNGHFFHRSCFRCH TCEATLWPGGYEQHPGDGHFYCLQH LPQTDHKAEGSDRGPESPELPTPSE NSMPPGLSTPTASQEGAGPVPDPSQ PTRRQIRLSSPERQRLSSLNLTPDP EMEPPPKPPRSCSALARHALESSFV GWGLPVQSPQALVAMEKEEKESPFS SEEEEEDVPLDSDVEQALQTFAKTS GTMNNYPTWRRTLLRRAKEEEMKRF CKAQTIQRRLNEIEAALRELEAEGV KLELALRRQSSSPEQQKKLWVGQLL QLVDKKNSLVAEEAELMITVQELNL EEKQWQLDQELRGYMNREENLKTAA DRQAEDQVLRKLVDLVNQRDALIRF QEERRLSELALGTGAQGTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol

Gene Information

• Gene Name: MICAL1 microtubule associated monoxygenase, calponin and LIM domain containing 1 [ Homo sapiens (human) ]
• Official Symbol: MICAL1
• Synonyms: MICAL1; microtubule associated monoxygenase, calponin and LIM domain containing 1; NEDD9 interacting protein with calponin homology and LIM domains , NICAL; protein-methionine sulfoxide oxidase MICAL1; DKFZp434B1517; FLJ11937; FLJ21739; MICAL; CasL interacting molecule; molecule interacting with CasL protein 1; NEDD9 interacting protein with calponin homology and LIM domains; NEDD9-interacting protein with calponin homology and LIM domains; NICAL; MICAL-1
• Gene ID: 64780
• mRNA Refseq: NM_022765
• Protein Refseq: NP_073602
• MIM: 607129
• UniProt ID: Q8TDZ2