Recombinant Full Length Human MMP3 Protein, C-Flag-tagged
Cat.No. : | MMP3-890HFL |
Product Overview : | Recombinant Full Length Human MMP3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
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Description : | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 52.2 kDa |
AA Sequence : | MKSLPILLLLCVAVCSAYPLDGAAR GEDTSMNLVQKYLENYYDLEKDVKQ FVRRKDSGPVVKKIREMQKF LGLEVTGKLDSDTLEVMRKPRCGVP DVGHFRTFPGIPKWRKTHLTYRIVN YTPDLPKDAVDSAVEKALKV WEEVTPLTFSRLYEGEADIMISFAV REHGDFYPFDGPGNVLAHAYAPGPG INGDAHFDDDEQWTKDTTGT NLFLVAAHEIGHSLGLFHSANTEAL MYPLYHSLTDLTRFRLSQDDINGIQ SLYGPPPDSPETPLVPTEPV PPEPGTPANCDPALSFDAVSTLRGE ILIFKDRHFWRKSLRKLEPELHLIS SFWPSLPSGVDAAYEVTSKD LVFIFKGNQFWAIRGNEVRAGYPRG IHTLGFPPTVRKIDAAISDKEKNKT YFFVEDKYWRFDEKRNSMEP GFPKQIAEDFPGIDSKIDAVFEEFG FFYFFTGSSQLEFDPNAKKVTHTLK SNSWLNCTRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, Protease |
Gene Name : | MMP3 matrix metallopeptidase 3 [ Homo sapiens (human) ] |
Official Symbol : | MMP3 |
Synonyms : | SL-1; STMY; STR1; CHDS6; MMP-3; STMY1 |
Gene ID : | 4314 |
mRNA Refseq : | NM_002422.5 |
Protein Refseq : | NP_002413.1 |
MIM : | 185250 |
UniProt ID : | P08254 |
Products Types
◆ Recombinant Protein | ||
MMP3-1117P | Recombinant Pig MMP3 Protein, His-tagged | +Inquiry |
MMP3-555H | Recombinant Human MMP3 Protein, MYC/DDK-tagged | +Inquiry |
MMP3-1123H | Recombinant Human MMP3 Protein, His-tagged | +Inquiry |
Mmp3-10594M | Recombinant Mouse Mmp3 Protein, His (Fc)-Avi-tagged | +Inquiry |
MMP3-5433H | Recombinant Human MMP3 Protein, GST-tagged | +Inquiry |
◆ Native Protein | ||
MMP3-26C | Native Clostridium histolyticum Collagenase Type 3 Protein | +Inquiry |
◆ Lysates | ||
MMP3-4273HCL | Recombinant Human MMP3 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-0589 | MMP-3 Activity Assay Kit | +Inquiry |
Kit-2213 | MMP-3 Activity Fluorometric Assay Kit | +Inquiry |
Related Gene
Not For Human Consumption!
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Q&As (7)
Ask a questionMMP3 breaks down extracellular matrix components, aiding in tissue remodeling and repair.
MMP3 facilitates cancer metastasis by altering the tumor microenvironment and promoting invasion.
Changes in MMP3 activity can accelerate skin aging and contribute to dermatological conditions.
MMP3 influences cardiovascular health by affecting arterial wall remodeling and stability.
MMP3 contributes to arthritis progression by degrading joint cartilage and connective tissues.
MMP3 modulates inflammation, impacting tissue inflammation and repair processes.
MMP3 plays a role in wound healing by remodeling damaged tissues and aiding in repair.
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