Recombinant Full Length Human MS4A1 Protein, C-Flag-tagged

• Cat.No.: MS4A1-118HFL
• Product Overview: Recombinant Full Length Human MS4A1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 32.9 kDa
• AA Sequence: MTTPRNSVNGTFPAEPMKGPIAMQS GPKPLFRRMSSLVGPTQSFFMRESK TLGAVQIMNGLFHIALGGLL MIPAGIYAPICVTVWYPLWGGIMYI ISGSLLAATEKNSRKCLVKGKMIMN SLSLFAAISGMILSIMDILN IKISHFLKMESLNFIRAHTPYINIY NCEPANPSEKNSPSTQYCYSIQSLF LGILSVMLIFAFFQELVIAG IVENEWKRTCSRPKSNIVLLSAEEK KEQTIEIKEEVVGLTETSSQPKNEE DIEIIPIQEEEEEETETNFP
  EPPQDQESSPIENDSSPTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Hematopoietic cell lineage

Gene Information

• Gene Name: MS4A1 membrane spanning 4-domains A1 [ Homo sapiens (human) ]
• Official Symbol: MS4A1
• Synonyms: B1; S7; Bp35; CD20; FMC7; CVID5; LEU-16
• Gene ID: 931
• mRNA Refseq: NM_021950.4
• Protein Refseq: NP_068769.2
• MIM: 112210
• UniProt ID: P11836